[HTML][HTML] New approach methodologies in human regulatory toxicology–Not if, but how and when!
S Schmeisser, A Miccoli, M von Bergen… - Environment …, 2023 - Elsevier
The predominantly animal-centric approach of chemical safety assessment has increasingly
come under pressure. Society is questioning overall performance, sustainability, continued …
come under pressure. Society is questioning overall performance, sustainability, continued …
[HTML][HTML] Application of AOPs to assist regulatory assessment of chemical risks–Case studies, needs and recommendations
L Bajard, O Adamovsky, K Audouze, K Baken… - Environmental …, 2023 - Elsevier
While human regulatory risk assessment (RA) still largely relies on animal studies, new
approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative …
approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative …
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe
P Marx-Stoelting, G Rivière, M Luijten… - Archives of …, 2023 - Springer
Current approaches for the assessment of environmental and human health risks due to
exposure to chemical substances have served their purpose reasonably well. Nevertheless …
exposure to chemical substances have served their purpose reasonably well. Nevertheless …
Perfluoroalkyl and polyfluoroalkyl substances in groundwater used as a source of drinking water in the eastern United States
PB McMahon, AK Tokranov, LM Bexfield… - … science & technology, 2022 - ACS Publications
In 2019, 254 samples were collected from five aquifer systems to evaluate perfluoroalkyl and
polyfluoroalkyl substance (PFAS) occurrence in groundwater used as a source of drinking …
polyfluoroalkyl substance (PFAS) occurrence in groundwater used as a source of drinking …
[HTML][HTML] Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment
E Drakvik, R Altenburger, Y Aoki, T Backhaus… - Environment …, 2020 - Elsevier
The number of anthropogenic chemicals, manufactured, by-products, metabolites and
abiotically formed transformation products, counts to hundreds of thousands, at present …
abiotically formed transformation products, counts to hundreds of thousands, at present …
Regulatory assessment and risk management of chemical mixtures: challenges and ways forward
SK Bopp, A Kienzler, AN Richarz… - Critical Reviews in …, 2019 - Taylor & Francis
This paper summarizes current challenges, the potential use of novel scientific
methodologies, and ways forward in the risk assessment and risk management of mixtures …
methodologies, and ways forward in the risk assessment and risk management of mixtures …
The next frontier of environmental unknowns: substances of unknown or variable composition, complex reaction products, or biological materials (UVCBs)
Substances of unknown or variable composition, complex reaction products, or biological
materials (UVCBs) are over 70 000 “complex” chemical mixtures produced and used at …
materials (UVCBs) are over 70 000 “complex” chemical mixtures produced and used at …
[HTML][HTML] Health risks of solid waste management practices in rural Ghana: A semi-quantitative approach toward a solid waste safety plan
Inadequate solid waste management (SWM) can lead to environmental contamination and
human health risks. The health risks from poor SWM can vary based on specific practices …
human health risks. The health risks from poor SWM can vary based on specific practices …
[图书][B] Bioanalytical tools in water quality assessment
The first edition of Bioanalytical Tools in Water Quality Assessment was released in 2012.
The field has exploded since and the second edition updates and reviews the application of …
The field has exploded since and the second edition updates and reviews the application of …
Application of a framework for grouping and mixtures toxicity assessment of PFAS: A closer examination of dose-additivity approaches
Environmental occurrence and biomonitoring data for per-and polyfluoroalkyl substances
(PFAS) demonstrate that humans are exposed to mixtures of PFAS. This article presents a …
(PFAS) demonstrate that humans are exposed to mixtures of PFAS. This article presents a …