OrthoDB provides evolutionary and functional annotations of genes in a diverse sampling of
eukaryotes, prokaryotes, and viruses. Genomics continues to accelerate our exploration of …

Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of
their physiology. To facilitate explorations of mosquito biology, we have created Aegypti …

Programmable gene editing systems such as CRISPR-Cas have made mosquito genome
engineering more practical and accessible, catalyzing the development of cutting-edge …

Mosquitoes are vectors of many pathogens, including viruses, protozoans, and helminths,
spreading these pathogens to humans as well as to wild and domestic animals. As the …

Mosquitoes are prolific vectors of human pathogens, therefore a clear and accurate
understanding of the organization of their antimicrobial defenses is crucial for informing the …

Colombia aims to eliminate malaria by 2030 but remains one of the highest burden
countries in the Americas. Plasmodium vivax contributes half of all malaria cases, with its …

Aedes aegypti vectors the pathogens that cause dengue, yellow fever, Zika virus, and
chikungunya and is a serious threat to public health in tropical regions. Decades of work has …

The human proteome comprises of all of the proteins produced by the sequences translated
from the human genome with additional modifications in both sequence and function caused …

Background Canine heartworm is a widespread and potentially fatal mosquito-borne
disease caused by infections with the parasitic nematode, Dirofilaria immitis. We have …

Parasitic diseases caused by kinetoplastid parasites are a burden to public health
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …