Cell encapsulation: technical and clinical advances
Treating many chronic diseases will require a tight, minute-to-minute regulation of
therapeutic molecules that is currently not achievable with most pharmaceutical therapies …
therapeutic molecules that is currently not achievable with most pharmaceutical therapies …
Therapeutic cell encapsulation: ten steps towards clinical translation
Since the conception of cell microencapsulation, many scientists bet on this biotechnology
as they saw in it a promising alternative to protect transplanted cells from host …
as they saw in it a promising alternative to protect transplanted cells from host …
Sarcolipin is a key determinant of the basal metabolic rate, and its overexpression enhances energy expenditure and resistance against diet-induced obesity
SK Maurya, NC Bal, DH Sopariwala, M Pant… - Journal of Biological …, 2015 - ASBMB
Sarcolipin (SLN) is a novel regulator of sarcoplasmic reticulum Ca 2+ ATPase (SERCA) in
muscle. SLN binding to SERCA uncouples Ca 2+ transport from ATP hydrolysis. By this …
muscle. SLN binding to SERCA uncouples Ca 2+ transport from ATP hydrolysis. By this …
Autocrine function of aldehyde dehydrogenase 1 as a determinant of diet-and sex-specific differences in visceral adiposity
R Yasmeen, B Reichert, J Deiuliis, F Yang, A Lynch… - Diabetes, 2013 - Am Diabetes Assoc
Mechanisms for sex-and depot-specific fat formation are unclear. We investigated the role of
retinoic acid (RA) production by aldehyde dehydrogenase 1 (Aldh1a1,-a2, and-a3), the …
retinoic acid (RA) production by aldehyde dehydrogenase 1 (Aldh1a1,-a2, and-a3), the …
[HTML][HTML] Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane
R Farmahin, AM Gannon, R Gagné… - Food and Chemical …, 2019 - Elsevier
Hexabromocyclododecane (HBCD) is a brominated flame retardant found in the
environment and human tissues. The toxicological effects of HBCD exposure are not clearly …
environment and human tissues. The toxicological effects of HBCD exposure are not clearly …
Alginate microcapsules for drug delivery
Currently, conventional drug delivery systems do not provide adequate therapeutic profiles
for the management of multiple diseases. In this regard, cell encapsulation technology …
for the management of multiple diseases. In this regard, cell encapsulation technology …
Repurposing disulfiram as an anti-obesity drug: Treating and preventing obesity in high-fat-fed rats
Background and Objectives A drug repurposing strategy is an approach for identifying new
therapeutic uses for approved or investigational drugs. Thanks to the moderate cost of …
therapeutic uses for approved or investigational drugs. Thanks to the moderate cost of …
Polymeric antioxidant materials for treatment of inflammatory disorders
Reactive oxygen and nitrogen species (RONS) play a key role in physiological conditions as
signaling molecules for regulating homeostasis in the human body. However, abnormally …
signaling molecules for regulating homeostasis in the human body. However, abnormally …
Aldehyde dehydrogenase 1 a1 regulates energy metabolism in adipocytes from different species
Background Survival and longevity of xenotransplants depend on immune function and
ability to integrate energy metabolism between cells from different species. However …
ability to integrate energy metabolism between cells from different species. However …
[HTML][HTML] Immunometabolic effects of β-carotene and vitamin A in atherogenesis
A Blanco, J Amengual - Immunometabolism, 2024 - journals.lww.com
Carotenoids are a diverse group of lipids produced by photosynthetic organisms, and
therefore, these compounds are major components of healthy diets. Carotenoids are among …
therefore, these compounds are major components of healthy diets. Carotenoids are among …