Chronic inflammation generated by the tumor microenvironment is known to drive cancer
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …

Introduction: Optical biosensors, particularly those based on nanoplasmonics technology,
have emerged in recent decades as a potential solution for disease diagnostics and therapy …

Visual one-step simultaneous detection of low-abundance methylation is a crucial challenge
in early cancer diagnosis in a simple manner. Through the design of a closed split bipolar …

Cancer is one of the leading cause of death worldwide. Lung cancer (LCa) and prostate
cancer (PCa) are the two most common ones particularly among men with about 20% of …

Evanescent-wave optical biosensors have become an attractive alternative for the screening
of nucleic acids in the clinical context. They possess highly sensitive transducers able to …

DNA methylation is the predominant epigenetic modification that participates in many
fundamental cellular processes through posttranscriptional regulation of gene expression …

Biomarkers are unquestionable biological indicators for diagnosis and therapeutic
interventions providing appropriate classification of a wide range of health disorders and risk …

Circulating cell free DNA (cfDNA) methylation is a novel type of cancer biomarker, but its
minuscule proportion of total DNA makes proper analysis difficult in clinical samples. Herein …

Label-free biosensors, and especially those based on optical transducers like plasmonic or
silicon photonic systems, have positioned themselves as potential alternatives for rapid and …

DNA methylation as one of the most important epigenetic modifications has a critical role in
regulating gene expression and drug resistance in treating diseases such as cancer …