Nalmefene hydrochloride was first discovered as an opioid antagonist derivative of
naltrexone in 1975. It is among the most potent opioid antagonists currently on the market …

Background Few studies have previously evaluated the long-term impact of initiating the
combined use of alcohol and cocaine early-in-life during adolescence. Our preclinical study …

Ketamine, initially developed as a safer alternative to phencyclidine, has emerged as a
groundbreaking treatment in psychiatric practice. It gained popularity after its approval by the …

The history of ketamine began in the 1960s. Ketamine is a specific anesthetic drug that
exhibits analgesia, has a stabilizing impact on the cardiovascular system and does not …

Ketamine is a fast-acting N-methyl-D-aspartate (NMDA) receptor antagonist that can be
used in a range of clinical scenarios in the pre-hospital setting and emergency department …

Le Trouble de l'Usage d'Alcool (TUA) est une maladie psychiatrique caractérisée par une
consommation chronique et excessive d'alcool malgré des conséquences négatives sur la …

Alcohol use disorder is a common mental health issue with life-threatening consequences
like sustaining polytrauma while driving under the influence of alcohol. Such patients …

Few studies have previously evaluated the long-term impact of initiating the combined use of
alcohol and cocaine early-in-life during adolescence. Our preclinical study characterized …

Major depressive disorder (MDD) is one of the most common mental health disorders in the
United States (US) and is a major cause of disability. Approximately 67% of patients with …

The use of alcohol in the Czech Republic is socially accepted, and worldwide we reach the
top ranks in the annual intake of pure alcohol per adult. The consequence is a high …