Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

A Levin, M Tonelli, J Bonventre, J Coresh, JA Donner… - The Lancet, 2017 - thelancet.com
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

IgA nephropathy: an interesting autoimmune kidney disease

A Rajasekaran, BA Julian, DV Rizk - The American journal of the medical …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

K Kiryluk, E Sanchez-Rodriguez, XJ Zhou, F Zanoni… - Nature …, 2023 - nature.com
IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular
deposition of IgA. Here we performed a genome-wide association study of 10,146 kidney …

IgA nephropathy

JC Rodrigues, M Haas, HN Reich - Clinical Journal of the …, 2017 - journals.lww.com
IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international
collaborative efforts have led to important discoveries that have improved our understanding …

CKD prevalence varies across the European general population

K Brück, VS Stel, G Gambaro, S Hallan… - Journal of the …, 2016 - journals.lww.com
CKD prevalence estimation is central to CKD management and prevention planning at the
population level. This study estimated CKD prevalence in the European adult general …

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis

G Musso, R Gambino, JH Tabibian, M Ekstedt… - PLoS …, 2014 - journals.plos.org
Background Chronic kidney disease (CKD) is a frequent, under-recognized condition and a
risk factor for renal failure and cardiovascular disease. Increasing evidence connects non …

IgA nephropathy

RJ Wyatt, BA Julian - New England Journal of Medicine, 2013 - Mass Medical Soc
IgA nephropathy is a common glomerular disease that is an important cause of kidney
failure. This review discusses advances in the therapy and understanding of the molecular …

IgA nephropathy

KN Lai, SCW Tang, FP Schena, J Novak… - Nature reviews Disease …, 2016 - nature.com
Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

K Kiryluk, Y Li, F Scolari, S Sanna-Cherchi, M Choi… - Nature …, 2014 - nature.com
We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the
most common form of glomerulonephritis, with discovery and follow-up in 20,612 individuals …

Current understanding of the role of complement in IgA nephropathy

N Maillard, RJ Wyatt, BA Julian, K Kiryluk… - Journal of the …, 2015 - journals.lww.com
Complement activation has a role in the pathogenesis of IgA nephropathy, an autoimmune
disease mediated by pathogenic immune complexes consisting of galactose-deficient IgA1 …