Importance of cytokines in murine allergic airway disease and human asthma

FD Finkelman, SP Hogan, GKK Hershey… - The Journal of …, 2010 - journals.aai.org
Asthma is a common, disabling inflammatory respiratory disease that has increased in
frequency and severity in developed nations. We review studies of murine allergic airway …

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action

L Ionescu, RN Byrne, T van Haaften… - … of Physiology-Lung …, 2012 - journals.physiology.org
Mortality and morbidity of acute lung injury and acute respiratory distress syndrome remain
high because of the lack of pharmacological therapies to prevent injury or promote repair …

[HTML][HTML] Metabolites of seaweeds as potential agents for the prevention and therapy of influenza infection

N Besednova, T Zaporozhets, T Kuznetsova… - Marine drugs, 2019 - mdpi.com
Context: Seaweed metabolites (fucoidans, carrageenans, ulvans, lectins, and polyphenols)
are biologically active compounds that target proteins or genes of the influenza virus and …

[HTML][HTML] Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early …

R Eccles, C Meier, M Jawad, R Weinmüllner… - Respiratory …, 2010 - Springer
Background The common cold, the most prevalent contagious viral disease in humans still
lacks a safe and effective antiviral treatment. Iota-Carrageenan is broadly active against …

Effect of mesenchymal stem cells on inhibiting airway remodeling and airway inflammation in chronic asthma

X Ge, C Bai, J Yang, G Lou, Q Li… - Journal of Cellular …, 2013 - Wiley Online Library
Previous studies proved that bone marrow‐derived mesenchymal stem cells (BMSCs) could
improve a variety of immune‐mediated disease by its immunomodulatory properties. In this …

[HTML][HTML] PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production

IP Lewkowich, S Lajoie, SL Stoffers, Y Suzuki… - Mucosal …, 2013 - Elsevier
Studies examining the role of programmed death 1 (PD-1) ligand 2 (PD-L2)/PD-1 in asthma
have yielded conflicting results. To clarify its role, we examined the PD-L2 expression in …

Paracrine effects and heterogeneity of marrow-derived stem/progenitor cells: relevance for the treatment of respiratory diseases

M Conese, A Carbone, S Castellani, S Di Gioia - Cells Tissues Organs, 2013 - karger.com
Stem cell-based treatment may represent a hope for the treatment of acute lung injury and
pulmonary fibrosis, and other chronic lung diseases, such as cystic fibrosis, asthma and …

Intratracheal transplantation of bone marrow‐derived mesenchymal stem cells reduced airway inflammation and up‐regulated CD4+CD25+ regulatory T cells in …

X Ge, C Bai, J Yang, G Lou, Q Li… - Cell biology …, 2013 - Wiley Online Library
Mesenchymal stem cells attenuate the severity of lung injury due to their immunomodulatory
properties. The effect of bone marrow‐derived mesenchymal stem cells on asthma is seldom …

Cytokines and cytokine-specific therapy in asthma

D Desai, C Brightling - Advances in clinical chemistry, 2012 - books.google.com
Asthma is increasing in prevalence worldwide. It is characterized by typical symptoms and
variable airway obstruction punctuated with episodes of worsening symptoms known as …

[HTML][HTML] Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen

RH Jan, TY Lin, YC Hsu, SS Lee, SY Lo, M Chang… - BMC immunology, 2011 - Springer
Background Ganoderma lucidum-derived polysaccharide (PS-G) can rapidly and effectively
promote the activation and maturation of immature dendritic cells (DCs), suggesting that PS …