Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Biobased covalent adaptable networks: towards better sustainability of thermosets

XL Zhao, PX Tian, YD Li, JB Zeng - Green Chemistry, 2022 - pubs.rsc.org
Thermosets have many advantages such as excellent mechanical properties, dimensional
stability, and chemical and environmental resistance, but suffer from unsustainability …

Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release

N Kamaly, B Yameen, J Wu, OC Farokhzad - Chemical reviews, 2016 - ACS Publications
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

Smart nanocarriers as an emerging platform for cancer therapy: A review

M Kenchegowda, M Rahamathulla, U Hani, MY Begum… - Molecules, 2021 - mdpi.com
Cancer is a group of disorders characterized by uncontrolled cell growth that affects around
11 million people each year globally. Nanocarrier-based systems are extensively used in …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: a review

M Kanamala, WR Wilson, M Yang, BD Palmer, Z Wu - Biomaterials, 2016 - Elsevier
As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

Stimuli-responsive nanocarriers for drug delivery

S Mura, J Nicolas, P Couvreur - Nature materials, 2013 - nature.com
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive
devices that deliver a drug in spatial-, temporal-and dosage-controlled fashions have …

pH-sensitive biomaterials for drug delivery

S Zhuo, F Zhang, J Yu, X Zhang, G Yang, X Liu - Molecules, 2020 - mdpi.com
The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

pH-responsive polymer nanomaterials for tumor therapy

S Chu, X Shi, Y Tian, F Gao - Frontiers in oncology, 2022 - frontiersin.org
The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …