Application of metabolomics in the diagnosis of non-alcoholic fatty liver disease and the treatment of traditional Chinese medicine
M Shao, Y Lu, H Xiang, J Wang, G Ji… - Frontiers in Pharmacology, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease around
the world, and it often coexists with insulin resistance-related diseases including obesity …
the world, and it often coexists with insulin resistance-related diseases including obesity …
Pharmacological evaluation of anti-arthritic potential of terpinen-4-ol using in vitro and in vivo assays
Terpinen 4-ol, a phytochemical is a monoterpene which has been reported for its anti-
inflammatory effect. Present research was planned to check its effect against arthritis through …
inflammatory effect. Present research was planned to check its effect against arthritis through …
Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
P Glajzner, A Bernat… - Frontiers in …, 2024 - frontiersin.org
Drug repurposing (repositioning) is a dynamically-developing area in the search for effective
therapy of infectious diseases. Repositioning existing drugs with a well-known …
therapy of infectious diseases. Repositioning existing drugs with a well-known …
Rosuvastatin attenuates rheumatoid arthritis-associated manifestations via modulation of the pro-and anti-inflammatory cytokine network: a combination of in vitro and …
The current investigation employed rosuvastatin for evaluation as an antiarthritic agent by in
vitro and in vivo studies. In vitro studies comprised egg albumin and bovine serum albumin …
vitro and in vivo studies. In vitro studies comprised egg albumin and bovine serum albumin …
Attenuation of CFA-induced chronic inflammation by a bicyclic monoterpene fenchone targeting inducible nitric oxide, prostaglandins, C-reactive protein and urea
Fenchone (a bicyclic monoterpene) is present in the essential oils of plant species like
Foeniculum vulgare and Peumus boldus and is used to treat GIT disorders. Research …
Foeniculum vulgare and Peumus boldus and is used to treat GIT disorders. Research …
Assessment of antiarthritic potential of Asparagus dumosus using formaldehyde and CFA-induced arthritic models in rats via modulation of oxidative stress …
N Nazar, MH Mehmood, R Siddique, MN Faisal - Inflammopharmacology, 2024 - Springer
Medicinal plants play a pivotal role in the prevention of chronic non-communicable diseases
including arthritis. Despite the traditional use of Asparagus dumosus in arthritis, it has not …
including arthritis. Despite the traditional use of Asparagus dumosus in arthritis, it has not …
Appraisal of the antiarthritic potential of prazosin via inhibition of proinflammatory cytokine TNF-α: a key player in rheumatoid arthritis
Prazosin, a selective α1 adrenergic receptor antagonist, with documented anti-inflammatory
potential, was evaluated for its antiarthritic efficacy by targeting specifically TNF-α. The …
potential, was evaluated for its antiarthritic efficacy by targeting specifically TNF-α. The …
Linalool: Monoterpene alcohol effectiveness in chronic synovitis through lowering Interleukin-17, spleen and thymus indices
Interleukin-17 has a positive role in the initial induction and late chronic phases of many
inflammatory disorders like arthritis. This cytokine has a strong option for therapeutic …
inflammatory disorders like arthritis. This cytokine has a strong option for therapeutic …
Novel antiarthritic mechanisms of azelaic acid against CFA-induced arthritis in rats by modulating pro-and anti-inflammatory cytokines network
NT Sial, A Malik, U Iqbal, MH Mehmood… - …, 2024 - Springer
An immunologic system attacking the body's own tissues is a hallmark of autoimmune
disorders, which encompass a wide range of unique conditions. Numerous essential …
disorders, which encompass a wide range of unique conditions. Numerous essential …
Enalapril attenuated CFA provoked arthritic manifestation by modulating proinflammatory and anti-inflammatory cytokine network
Enalapril with documented anti-inflammatory potential was evaluated in current investigation
to explore its anti-arthritic efficacy. For anti-arthritic evaluation of enalapril, CFA-instigated …
to explore its anti-arthritic efficacy. For anti-arthritic evaluation of enalapril, CFA-instigated …