More than three decades after the discovery of HLA-B27 as a major genetic clue to the
origins of ankylosing spondylitis, much has been learned about pathogenesis. However, the …

Rheumatoid arthritis (RA) is a disease well characterised by proinflammatory cytokine
secretion (particularly tumour necrosis factor, interferon gamma, interleukin (IL) 1, and IL6) …

Ankylosing spondylitis (AS) is a chronic, inflammatory, rheumatological disease affecting
primarily the sacroiliac joint and vertebral column, with an etiology that remains obscure …

Abstract Objective Peripheral spondylarthritis (SpA) is characterized by macrophages that
express CD163, a marker of alternative activation (M2). The purpose of this study was to …

A role for NK cells in the regulation of autoimmunity has been demonstrated. Since there is a
strong association between Ankylosing Spondylitis (AS) and HLA-B27, which is specifically …

There is a high co-morbidity between chronic inflammatory disorders and depression.
Proinflammatory cytokines like TNF-α seem to play a central role in the pathogenesis of …

OBJECTIVES: The aim was to access the effects of treatment on bone mineral density (BMD)
by treatment agents in patients with ankylosing spondylitis (AS). METHODS: We analyzed …

Our aim was to assess the phenotype of T‐cell subsets in patients with ankylosing
spondylitis (AS), a chronic inflammatory rheumatic disease. In addition, we also tested short …

Purpose This study aims to investigate any associations of the proinflammatory cytokine IL-1
in treated patients with inflammatory bowel disease (IBD) and the enteropathic seronegative …

BACKGROUND: To understand the cytokine levels in different disease activities of patients
with ankylosing spondylitis (AS), we measured proinflammatory and antiinflammatory …