Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] Growth hormone (s), testosterone, insulin-like growth factors, and cortisol: roles and integration for cellular development and growth with exercise

WJ Kraemer, NA Ratamess, WC Hymer… - Frontiers in …, 2020 - frontiersin.org
Hormones are largely responsible for the integrated communication of several physiological
systems responsible for modulating cellular growth and development. Although the specific …

[HTML][HTML] Regulation of skeletal muscle glucose transport and glucose metabolism by exercise training

PL Evans, SL McMillin, LA Weyrauch, CA Witczak - Nutrients, 2019 - mdpi.com
Aerobic exercise training and resistance exercise training are both well-known for their
ability to improve human health; especially in individuals with type 2 diabetes. However …

[HTML][HTML] An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy

C Lim, EA Nunes, BS Currier, JC Mcleod… - Medicine and science …, 2022 - ncbi.nlm.nih.gov
Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …

[HTML][HTML] Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans

S Joanisse, C Lim, J McKendry, JC Mcleod… - …, 2020 - ncbi.nlm.nih.gov
Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …

[HTML][HTML] A systematic review examining the approaches used to estimate interindividual differences in trainability and classify individual responses to exercise training

JT Bonafiglia, N Preobrazenski, BJ Gurd - Frontiers in physiology, 2021 - frontiersin.org
Background: Many reports describe statistical approaches for estimating interindividual
differences in trainability and classifying individuals as “responders” or “non-responders.” …

The concept of skeletal muscle memory: Evidence from animal and human studies

T Snijders, T Aussieker, A Holwerda, G Parise… - Acta …, 2020 - Wiley Online Library
Within the current paradigm of the myonuclear domain theory, it is postulated that a linear
relationship exists between muscle fibre size and myonuclear content. The myonuclear …

[HTML][HTML] Sarcoplasmic hypertrophy in skeletal muscle: a scientific “unicorn” or resistance training adaptation?

MD Roberts, CT Haun, CG Vann, SC Osburn… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fibers are multinucleated cells that contain mostly myofibrils suspended in
an aqueous media termed the sarcoplasm. Select evidence suggests sarcoplasmic …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Ketone bodies attenuate wasting in models of atrophy

AP Koutnik, AM Poff, NP Ward… - Journal of cachexia …, 2020 - Wiley Online Library
Abstract Background Cancer Anorexia Cachexia Syndrome (CACS) is a distinct atrophy
disease negatively influencing multiple aspects of clinical care and patient quality of life …