The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …

Objective: There is burgeoning interest in augmentation strategies for improving inadequate
response to antidepressants. The adjunctive use of standardized pharmaceutical-grade …

In this article, we aimed to assess the efficacy of adjunctive administration of nutritional
supplements to antidepressants by means of a systematic review and meta-analysis. The …

Mood disorders such as major depressive disorder and bipolar disorder are chronic and
recurrent illnesses that cause significant disability and affect approximately 350 million …

There is robust evidence that major depression (MDD) is accompanied by a low-grade
activation of the immune-inflammatory response system, which is involved in the …

Postpartum depression (PPD) is a challenging psychological disorder faced by 10–30% of
mothers across the globe. In India, it occurs among 22% of mothers. Its aetiology and …

Context Zinc is an essential trace mineral required for the function of brain and neural
structures. The role of zinc supplementation in the prevention and treatment of depression …

Interaction between the gastrointestinal tract (GI) and brain functions has recently become a
topic of growing interest in psychiatric research. These multidirectional interactions take …

Many neurodegenerative and neuropsychiatric disorders have been reported to coincide
with the dysregulation of metal ions in the body and central nervous system. However, in …

Preclinical and clinical studies have demonstrated that zinc possesses antidepressant
properties and that it may augment the therapy with conventional, that is, monoamine …