Cognitive impairment is an increasingly recognized major cause of chronic disability and is
commonly found in patients with chronic kidney disease (CKD). Knowledge of the …

Background: Given the increasing worldwide prevalence of chronic kidney disease (CKD), it
is critical to decrease the associated risk of debilitating vascular complications, including …

Background Sepsis-associated brain dysfunction (SABD) is associated with high morbidity
and mortality. The pathophysiology of SABD is multifactorial. One hypothesis is that impaired …

Background: Cognitive impairment, increasingly recognized as a major social burden, is
commonly found in chronic kidney disease (CKD) patients. Summary: Vascular damage …

The kidney and the brain, as high-flow end organs relying on autoregulatory mechanisms,
have unique anatomic and physiological hemodynamic properties. Similarly, the two organs …

Chronic kidney disease (CKD) affects more than 37 million American adults. Adult-onset
CKD is typically attributed to acquired comorbidities such as aging, type II diabetes, and …

When present in coding regions, tandem repeats (TRs) may have large effects on protein
structure and function contributing to health and disease. We use a family-based design to …

Background CKD is associated with abnormalities in cerebral blood flow, cerebral
neurochemical concentrations, and white matter integrity. Each of these is associated with …

To investigate functional connectivity (FC) changes in end-stage renal disease (ESRD)
patients with and without cognitive impairment (CI) by using resting-state functional …

Background Altered cerebral blood flow (CBF) and amplitude of low-frequency fluctuation
(ALFF) have been reported in hemodialysis patients. However, neurovascular coupling …