Breast cancer is one of the most common malignant tumors in women worldwide, and thus, it
is important to enhance its treatment efficacy [1]. Copper has emerged as a critical trace …

Pyroptosis has been reported to improve the immunosuppressive tumor microenvironment
and may be a strategy to enhance osteosarcoma treatment. The extent to which modulation …

Ovarian function suppression is the current pharmacotherapy of endometriosis with limited
benefit and adverse effects. New therapeutic strategies other than hormonal therapy are …

Lung adenocarcinoma (LUAD) has become the most prevalent histologic subset of primary
lung cancer, and effective innovative prognostic models are needed to enhance the …

Metabolic disorder is a major characteristic of cancer cells, and controlling genes involved in
metabolic shifts can be an effective strategy for cancer treatment. Andrographolide (AG), a …

Most cancer cells primarily produce their energy through a high rate of glycolysis followed by
lactic acid fermentation even in the presence of abundant oxygen. Pyruvate dehydrogenase …

Ilimaquinone (IQ), a metabolite found in marine sponges, has been reported to have a
number of biological properties, including potential anticancer activity against colon cancer …

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide.
Targeted therapy against the epidermal growth factor receptor (EGFR) is a promising …

Background Neuroblastoma (NB) is the most frequent solid tumor in pediatrics, which
accounts for roughly 15% of cancer-related mortality in children. NB exhibited genetic …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors
expressed in the skin. Three PPAR isotypes, α (NRC1C1), β or δ (NRC1C2) and γ …