Collective cell migration critically depends on cell–cell interactions coupled to a dynamic
actin cytoskeleton. Important cell–cell adhesion receptor systems implicated in controlling …

Over the past half-century, we have gained significant insights into the molecular biology of
long-term memory storage at the level of the synapse. In recent years, our understanding of …

Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

The mitogen-activated protein kinase (MAPK) cascade that leads to the activation of
extracellular signal-regulated kinases-1 and-2 (ERK1 and ERK2) has a key role in the …

Although Ca 2+-stimulated cAMP response element binding protein–(CREB-) dependent
transcription has been implicated in growth, differentiation, and neuroplasticity, mechanisms …

NOBEL LECTURE: The Molecular Biology of Memory Storage: A Dialog Between Genes and
Synapses Page 1 Bioscience Reports, Vol. 21, No. 5, October 2001 ( 2002) NOBEL LECTURE …

Most molecular and cellular studies of cognitive function have focused on either normal or
pathological states, but recent research with transgenic mice has started to address the …

Extracellular-signal-regulated kinases (ERKs) are emerging as important regulators of
neuronal function. Recent advances have increased our understanding of ERK signalling at …

Long-term facilitation of the sensory to motor synapse in Aplysia requires gene expression.
While some transcription factors involved in long-term facilitation are phosphorylated by …

Outer hair cells (OHCs) of the mammalian cochlea actively change their cell length in
response to changes in membrane potential. This electromotility, thought to be the basis of …