Effects of molecular crowding on the structures, interactions, and functions of nucleic acids

S Nakano, D Miyoshi, N Sugimoto - Chemical reviews, 2014 - ACS Publications
Nucleic acids are excellent at recognizing complementary sequences through the formation
of Watson− Crick base pairs. Since the base pairing enables the highly selective …

The physicochemical aspects of DNA sensing using electrochemical methods

C Batchelor-McAuley, GG Wildgoose… - Biosensors and …, 2009 - Elsevier
As our understanding of the human genome increases there is an ever expanding demand
for fast, sensitive and selective methods of DNA analysis. Due to the low associated …

Carbon nanotube-based label-free electrochemical biosensor for sensitive detection of miRNA-24

F Li, J Peng, J Wang, H Tang, L Tan, Q Xie… - Biosensors and …, 2014 - Elsevier
The recent findings concerning the function of microRNAs (miRNAs) and the relationship
between miRNA levels with specific disease highlight the need for miRNA detection. In this …

DNA surface hybridization: comparison of theory and experiment

D Irving, P Gong, R Levicky - The Journal of Physical Chemistry B, 2010 - ACS Publications
The design and interpretation of surface hybridization assays is complicated by poorly
understood aspects of the interfacial environment that cause both kinetic and …

Effects of probe length, probe geometry, and redox-tag placement on the performance of the electrochemical E-DNA sensor

AA Lubin, B Vander Stoep Hunt, RJ White… - Analytical …, 2009 - ACS Publications
Previous work has described several reagentless, electrochemical DNA (E-DNA) sensing
architectures comprised of an electrode-immobilized, redox-tagged probe oligonucleotide …

A model for structure and thermodynamics of ssDNA and dsDNA near a surface: A coarse grained approach

J Ambia-Garrido, A Vainrub, BM Pettitt - Computer physics communications, 2010 - Elsevier
New methods based on surfaces or beads have allowed measurement of properties of
single DNA molecules in very accurate ways. Theoretical coarse grained models have been …

Understanding oligonucleotide hybridization and the role of anchoring on the single-walled carbon nanotube corona phase for viral sensing applications

J Cui, X Gong, SY Cho, X Jin, S Yang… - The Journal of …, 2022 - ACS Publications
Semiconducting single-walled carbon nanotubes (SWCNTs) with tailored corona phases
(CPs), or surface-adsorbed molecules, have emerged as a promising interface for sensing …

Prominent enhancement of peptide-mediated targeting efficiency for human hepatocellular carcinomas with composition-engineered protein corona on gold …

M Liu, W Lai, M Chen, P Wang, J Liu, X Fang… - Colloids and Surfaces A …, 2023 - Elsevier
We examined the feasibility of optimizing protein corona composition to improve the
targeting efficiency of a tumor targeting peptide (Pep2) functionalized AuNPs (Au-Pep2) by …

[HTML][HTML] Microfluidic chip for multiple detection of miRNA biomarkers in breast cancer based on three-segment hybridization

Y Gao, L Qiang, Y Chu, Y Han, Y Zhang, L Han - AIP Advances, 2020 - pubs.aip.org
It is urgent to establish a fast, convenient, accurate, and low-cost miRNA quantitative
detection platform, which is important in disease development and the early diagnosis of …

Sexual dimorphism and aging in the human hyppocampus: identification, validation, and impact of differentially expressed genes by factorial microarray and network …

DV Guebel, NV Torres - Frontiers in aging neuroscience, 2016 - frontiersin.org
Motivation: In the brain of elderly-healthy individuals, the effects of sexual dimorphism and
those due to normal aging appear overlapped. Discrimination of these two dimensions …