[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: A systematic review

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Advances in the development of new biomarkers for Alzheimer's disease

TO Klyucherev, P Olszewski, AA Shalimova… - Translational …, 2022 - Springer
Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …

Spectral-domain OCT measurements in Alzheimer's disease: a systematic review and meta-analysis

VTT Chan, Z Sun, S Tang, LJ Chen, A Wong, CC Tham… - Ophthalmology, 2019 - Elsevier
Topic OCT is a noninvasive tool to measure specific retinal layers in the eye. The
relationship of retinal spectral-domain (SD) OCT measurements with Alzheimer's disease …

[HTML][HTML] Alzheimer's disease pathophysiology in the retina

BP Gaire, Y Koronyo, DT Fuchs, H Shi… - Progress in Retinal and …, 2024 - Elsevier
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Retinal changes in Alzheimer's disease—integrated prospects of imaging, functional and molecular advances

VB Gupta, N Chitranshi, J den Haan, M Mirzaei… - Progress in retinal and …, 2021 - Elsevier
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Alzheimer's retinopathy: seeing disease in the eyes

N Mirzaei, H Shi, M Oviatt, J Doustar… - Frontiers in …, 2020 - frontiersin.org
The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …

Optical coherence tomography in Alzheimer's disease and other neurodegenerative diseases

J Doustar, T Torbati, KL Black, Y Koronyo… - Frontiers in …, 2017 - frontiersin.org
Over the past decade, a surge of evidence has documented various pathological processes
in the retina of patients suffering from mild cognitive impairment, Alzheimer's disease (AD) …

Retinal vasculopathy in Alzheimer's disease

H Shi, Y Koronyo, A Rentsendorj, DT Fuchs… - Frontiers in …, 2021 - frontiersin.org
The retina has been increasingly investigated as a site of Alzheimer's disease (AD)
manifestation for over a decade. Early reports documented degeneration of retinal ganglion …

Changes in visual function and retinal structure in the progression of Alzheimer's disease

E Salobrar-García, R de Hoz, AI Ramírez… - PloS one, 2019 - journals.plos.org
Background Alzheimer's Disease (AD) can cause degeneration in the retina and optic nerve
either directly, as a result of amyloid beta deposits, or secondarily, as a result of the …