Tertiary lymphoid structures in diseases: immune mechanisms and therapeutic advances
L Zhao, S Jin, S Wang, Z Zhang, X Wang… - … and Targeted Therapy, 2024 - nature.com
Tertiary lymphoid structures (TLSs) are defined as lymphoid aggregates formed in non-
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …
Tertiary lymphoid structures in cancer: maturation and induction
Y Chen, Y Wu, G Yan, G Zhang - Frontiers in Immunology, 2024 - frontiersin.org
Tertiary lymphoid structure (TLS) is an ectopic lymphocyte aggregate formed in peripheral
non-lymphoid tissues, including inflamed or cancerous tissue. Tumor-associated TLS serves …
non-lymphoid tissues, including inflamed or cancerous tissue. Tumor-associated TLS serves …
Deciphering head and neck cancer microenvironment: single‐cell and spatial transcriptomics reveals human papillomavirus‐associated differences
H Lee, S Park, JH Yun, C Seo, JM Ahn… - Journal of Medical …, 2024 - Wiley Online Library
Human papillomavirus (HPV) is a major causative factor of head and neck squamous cell
carcinoma (HNSCC), and the incidence of HPV‐associated HNSCC is increasing. The role …
carcinoma (HNSCC), and the incidence of HPV‐associated HNSCC is increasing. The role …
Macrophages and tertiary lymphoid structures as indicators of prognosis and therapeutic response in cancer patients
L Niu, T Chen, A Yang, X Yan, F Jin, A Zheng… - Biochimica et Biophysica …, 2024 - Elsevier
Tertiary lymphoid structures (TLS) can reflect cancer prognosis and clinical outcomes in
various tumour tissues. Tumour-associated macrophages (TAMs) are indispensable …
various tumour tissues. Tumour-associated macrophages (TAMs) are indispensable …
T cell exhaustion initiates tertiary lymphoid structures and turbocharges cancer-immunity cycle
WP Lin, H Li, ZJ Sun - Ebiomedicine, 2024 - thelancet.com
Immune therapies represented by immune checkpoint blockade (ICB) have significantly
transformed cancer treatment. However, the effectiveness of these treatments depends on …
transformed cancer treatment. However, the effectiveness of these treatments depends on …
Intratumor tertiary lymphatic structure evaluation predicts the prognosis and immunotherapy response of patients with colorectal cancer
H Feng, S Zhang, Q Zhou, F Han, G Du… - Frontiers in …, 2024 - frontiersin.org
Background Immune checkpoint therapy, involving the programmed cell death 1 (PD-1)
monoclonal antibody, has revolutionized the treatment of cancer. Tertiary lymphatic structure …
monoclonal antibody, has revolutionized the treatment of cancer. Tertiary lymphatic structure …
[HTML][HTML] Tertiary lymphoid structures in head and neck squamous cell carcinoma
J Zhu, H Lu, K Wang, B Liu, J Yan - Translational Oncology, 2024 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy
worldwide. Smoking, drinking, and human papillomavirus (HPV) infection are the main risk …
worldwide. Smoking, drinking, and human papillomavirus (HPV) infection are the main risk …
[HTML][HTML] Exploring dendritic cell subtypes in cancer immunotherapy: unraveling the role of mature regulatory dendritic cells
O Badillo, L Helfridsson, J Niemi… - Upsala Journal of …, 2024 - ncbi.nlm.nih.gov
Dendritic cells (DCs) possess a specialized function in presenting antigens and play pivotal
roles in both innate and adaptive immune responses. Their ability to cross-present antigens …
roles in both innate and adaptive immune responses. Their ability to cross-present antigens …
Inflammatory markers as prognostic markers in patients with head and neck squamous cell carcinoma treated with immune checkpoint inhibitors: a systematic review …
Q Wang, X Yin, S Wang, H Lu - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Background Various inflammatory markers, including neutrophil-to-lymphocyte ratio (NLR),
monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and C-reactive …
monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and C-reactive …
Tertiary lymphoid structure in tumor microenvironment and immunotherapy of lung cancer
M Xie, X Lin, X Bao, Y Liang, H Deng, J Song… - Archivos de …, 2024 - Elsevier
Immune checkpoint inhibitors have opened an era of lung cancer therapy. However, a
notable disparity exists in the efficacy of immunotherapy among individual patients. The …
notable disparity exists in the efficacy of immunotherapy among individual patients. The …