Sleep disturbances, as well as sleep-wake rhythm disturbances, are typical symptoms of
Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative …

Background: Diabetes is one of the most challenging health problems in 21st century. It is a
group of endocrine-metabolic disorder characterized by high glucose level (hyperglycemia) …

This study (registered with PROSPERO, CRD42018085967) compares the efficacy (ie pro‐
cognitive effects) and acceptability of antidiabetic agents for Alzheimer's disease (AD) and …

The intracerebral level of the aggregation-prone peptide, amyloid-ß (Aß), is constantly
maintained by multiple clearance mechanisms, including several degradation enzymes, and …

Metformin, as an anti-hyperglycemic, is the main medicine for treating diabetes of type II.
However, its daily dose is high due to its incomplete absorption and short half-life, which …

The toxic conformer of amyloid β-protein (Aβ) ending at 42 (Aβ42), which contains a unique
turn conformation at amino acid residue positions 22 and 23 and tends to form oligomers …

Abstract Background/Objective: The purpose of this study was to evaluate the prevalence
and severity of skin involvement in children with IgA vasculitis (IgAV) and its relationship with …

Huntington's disease (HD) is a rare neurodegenerative disease that is accompanied by
skeletal muscle atrophy and cardiomyopathy. Tissues affected by HD (central nervous …

Background & Objective: Diabetes and neurodegenerative diseases (ND) are progressive
morbidities and represent a major public health burden. A growing body of evidence points …

Diabetes mellitus (DM) is known to be a risk factor for dementia, especially in the elderly
population, and close associations between diabetes and Alzheimer disease (AD) have …