Subpopulation dynamics of T and B lymphocytes in Sjögren's syndrome: implications for disease activity and treatment

Q Meng, J Ma, J Cui, Y Gu, Y Shan - Frontiers in Immunology, 2024 - frontiersin.org
Sjögren's syndrome (SS) is an autoimmune disorder primarily affecting the body's exocrine
glands, particularly the salivary and lacrimal glands, which lead to severe symptoms of dry …

Abnormal epigenetic regulations in the immunocytes of sjögren's syndrome patients and therapeutic potentials

P Li, M Han, X Zhao, G Ren, S Mei, C Zhong - Cells, 2022 - mdpi.com
Sjögren's syndrome (SjS), characterized by keratoconjunctivitis sicca and dry mouth, is a
common autoimmune disease, especially in middle-aged women. The …

[HTML][HTML] Belimumab treatment in autoimmune hepatitis and primary biliary cholangitis–a case series

M Kolev, AC Sarbu, B Möller, B Maurer, F Kollert… - Journal of translational …, 2023 - Elsevier
Background The majority of patients with autoimmune hepatitis (AIH) achieve complete
remission with established treatment regiments. In patients with intolerance or insufficient …

Altered DNA methylation pattern characterizes the peripheral immune cells of patients with autoimmune hepatitis

K Zachou, P Arvaniti, A Lyberopoulou… - Liver …, 2022 - Wiley Online Library
Abstract Background and Aims Little is known about the impact of DNA methylation
modifications on autoimmune hepatitis (AIH) pathogenesis and therapeutic response. We …

Reasons why women are more likely to develop primary biliary cholangitis

D Ma, J Ma, C Zhao, W Tai - Heliyon, 2024 - cell.com
Primary biliary cholangitis (PBC) is a chronic autoimmune disease of biliary stasis in which
immune factors cause the gradual destruction of small bile ducts, biliary stasis, and …

Primary Sjögren's syndrome: new perspectives on salivary gland epithelial cells

J Hou, Y Feng, Z Yang, Y Ding, D Cheng, Z Shi… - European Journal of …, 2024 - Springer
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease primarily affecting
exocrine glands such as the salivary glands, leading to impaired secretion and sicca …

Causal association between autoimmune liver disease and Sjögren's syndrome: A Mendelian randomization study

Y Li, J Wang, H Jiang, J Zhang, J Qi… - International Journal …, 2024 - Wiley Online Library
Background Observational studies have found an association between autoimmune liver
disease (AILD) and Sjögren's syndrome (SS). However, the causal relationship between the …

Therapeutic effect of modified zengye decoction on primary Sjogren's syndrome and its effect on plasma exosomal proteins

Y Zeng, X Peng, Y Wang, L Hou, W Ma… - Frontiers in …, 2022 - frontiersin.org
Background: Modified Zengye Decoction (MZD), a traditional Chinese medicine, is an
effective treatment for patients with primary Sjögren's syndrome (pSS). Purpose: To evaluate …

[PDF][PDF] Primary biliary cholangitis and Sjogren's syndrome: bi-directional Mendelian randomization analysis.

N Wang, Y Zhou, H Li, L Chen… - European Review for …, 2024 - europeanreview.org
OBJECTIVE: Observational studies have shown a higher prevalence of Sjogren's syndrome
(SjS) in patients with primary biliary cholangitis (PBC) than in the healthy population, but …

Epigenetic aspects of autoimmune diseases

WH Brooks, MI Arleevskaya… - Frontiers in Cell and …, 2022 - frontiersin.org
Genetics, environmental factors, and epigenetics all contribute to autoimmune disease onset
and progression (Gulati and Brunner, 2018). Most of the earlier research on autoimmune …