Antibody-dependent enhancement (ADE) of disease is a general concern for the
development of vaccines and antibody therapies because the mechanisms that underlie …

Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …

For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to
enhance viral replication in vitro and severe disease in animal models. Although suspected …

Zika virus (ZIKV) infection during pregnancy is linked to severe birth defects, but mother-to-
fetus transmission routes are unknown. We infected different primary cell types from mid-and …

Dengue is one of the most prevalent mosquito-borne diseases in the world, affecting an
estimated 390 million people each year, according to models. For the last two decades …

Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of
outbreaks accompanied by unexpectedly severe clinical complications brought this virus …

The recent association between Zika virus (ZIKV) infection during pregnancy and fetal
microcephaly has led to a renewed interest in the mechanisms by which vertically …

Background Dengue is a major public health issue worldwide and severe dengue (SD) is
life threatening. It is critical to triage patients with dengue infection in the early stage …

Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …