[HTML][HTML] Omics-based investigations of breast cancer

AN Neagu, D Whitham, P Bruno, H Morrissiey… - Molecules, 2023 - mdpi.com
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

[HTML][HTML] Proteomics-Based identification of dysregulated proteins and biomarker discovery in invasive ductal carcinoma, the most common breast cancer subtype

AN Neagu, D Whitham, L Seymour, N Haaker, I Pelkey… - Proteomes, 2023 - mdpi.com
Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …

Human breast tissue engineering in health and disease

MB Buchholz, DI Scheerman, R Levato… - EMBO Molecular …, 2024 - embopress.org
The human mammary gland represents a highly organized and dynamic tissue, uniquely
characterized by postnatal developmental cycles. During pregnancy and lactation, it …

[HTML][HTML] Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities

E Durán-Jara, M Del Campo, V Gutiérrez… - Biological Research, 2024 - Springer
Background Tumor-derived small extracellular vesicles (sEVs) can promote tumorigenic and
metastatic capacities in less aggressive recipient cells mainly through the biomolecules in …

Deciphering a proteomic signature for the early detection of breast cancer from breast milk: the role of quantitative proteomics

D Whitham, P Bruno, N Haaker, KF Arcaro… - Expert Review of …, 2024 - Taylor & Francis
Introduction Breast cancer is one of the most prevalent cancers among women in the United
States. Current research regarding breast milk has been focused on the composition and its …

Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

Advances in separation and identification of biologically important milk proteins and peptides

M Stastna - Electrophoresis, 2024 - Wiley Online Library
Milk is a rich source of biologically important proteins and peptides. In addition, milk contains
a variety of extracellular vesicles (EVs), including exosomes, that carry their own proteome …

Exploring novel protein-based biomarkers for advancing breast cancer diagnosis: A review

CJ Vellan, T Islam, S de Silva, NAM Taib… - Clinical …, 2024 - Elsevier
This review provides a contemporary examination of the evolving landscape of breast
cancer (BC) diagnosis, focusing on the pivotal role of novel protein-based biomarkers. The …

Knowledge of Non-Invasive Biomarkers of Breast Cancer, Risk Factors, and BSE Practices Among Nursing Undergraduates in Farasan Island, KSA

SF Sayed, HG Dailah, S Nagarajan… - SAGE Open …, 2024 - journals.sagepub.com
Background of the Study Mammograms are sometimes met with issues of overdiagnosis and
underdiagnosis; therefore, they are less reliable in identifying cancer in women with dense …

Cytotoxicity of T cells induced by recoverin-based fusion protein against tumor cells

Z Xia - 2024 - edoc.ub.uni-muenchen.de
Background: Cancer remains the leading cause of mortality and a significant barrier to
increasing life expectancy. Despite significant advancements in surgical and …