Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Abstract Interleukin-10 (IL-10) produced by a wide-variety of cells is a highly pleiotropic
cytokine. It has been implicated in the pathogenesis and/or development of autoimmune …

Members of the interleukin (IL)-10 family of cytokines play important roles in regulating
immune responses during host defense but also in autoimmune disorders, inflammatory …

Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

Since the discovery of interleukin-10 (IL-10) in the 1980s, a large body of work has led to its
recognition as a pleiotropic immunomodulatory cytokine that affects both the innate and …

Cancer immunotherapy is an evolving field of research. Cytokines have been
conceptualized as an anticancer therapy for longer than most other cancer immunotherapy …

The presence of activated intratumoral T cells correlates clinically with better prognosis in
patients with cancer. Although tumor vaccines can increase the number of tumor-specific …

Classification of cytokines as pro-versus anti-inflammatory might not apply to the pleiotropic
effects of interleukin-10 (IL-10). Several reports suggest that IL-10 enhances the function of …

Abstract Although interleukin-10 (IL-10) is commonly regarded as an anti-inflammatory,
immunosuppressive cytokine that favors tumor escape from immune surveillance, a wealth …

Interleukin-10 (IL-10) is a pleiotropic cytokine that modulates the function of several adaptive
immunity-related cells. Although generally considered an immunosuppressive molecule, IL …