The nuclear pore complex: birth, life, and death of a cellular behemoth

E Dultz, M Wojtynek, O Medalia, E Onischenko - Cells, 2022 - mdpi.com
Nuclear pore complexes (NPCs) are the only transport channels that cross the nuclear
envelope. Constructed from~ 500–1000 nucleoporin proteins each, they are among the …

Global profiling of protein complex dynamics with an experimental library of protein interaction markers

C Dörig, C Marulli, T Peskett, N Volkmar… - Nature …, 2024 - nature.com
Methods to systematically monitor protein complex dynamics are needed. We introduce
serial ultrafiltration combined with limited proteolysis-coupled mass spectrometry (FLiP–MS) …

Nuclear basket proteins regulate the distribution and mobility of nuclear pore complexes in budding yeast

J Zsok, F Simon, G Bayrak, L Isaki, N Kerff… - Molecular Biology of …, 2024 - molbiolcell.org
Nuclear pore complexes (NPCs) mediate all traffic between the nucleus and the cytoplasm
and are among the most stable protein assemblies in cells. Budding yeast cells carry two …

[PDF][PDF] Nuclear mRNA export

S Chen, Q Jiang, J Fan… - Acta Biochim Biophys …, 2024 - pdfs.semanticscholar.org
In eukaryotic cells, gene expression begins with transcription in the nucleus, followed by the
maturation of messenger RNAs (mRNAs). These mRNA molecules are then exported to the …

UvHOS3‐mediated histone deacetylation is essential for virulence and negatively regulates ustilaginoidin biosynthesis in Ustilaginoidea virens

B Wang, G Duan, L Liu, Z Long, X Bai… - Molecular Plant …, 2024 - Wiley Online Library
Ustilaginoidea virens is the causal agent of rice false smut, which has recently become one
of the most important rice diseases worldwide. Ustilaginoidins, a major type of mycotoxins …

A Yeast Mitotic Tale for the Nucleus and the Vacuoles to Embrace

S Santana-Sosa, E Matos-Perdomo… - International Journal of …, 2023 - mdpi.com
The morphology of the nucleus is roughly spherical in most eukaryotic cells. However, this
organelle shape needs to change as the cell travels through narrow intercellular spaces …

Fission yeast essential nuclear pore protein Nup211 regulates the expression of genes involved in cytokinesis

D Kamel, A Sookdeo, A Ikenouchi, H Zhong - PloS one, 2024 - journals.plos.org
Nuclear pore proteins control nucleocytoplasmic transport; however, certain nucleoporins
play regulatory roles in activities such as transcription and chromatin organization. The …

Cell cycle regulated expression of the WHI7 Start repressor gene

C Ros-Carrero, M Gomar-Alba, JC Igual - Cell Cycle, 2024 - Taylor & Francis
Periodic transcriptional waves along the cell cycle ensure the accurate progression of the
different cell cycle phases through the timely regulated expression of cell cycle proteins. The …

Gene-specific RNA homeostasis revealed by perturbation of coactivator complexes

F Forouzanfar, D Plassard, A Furst, D Moreno… - …, 2024 - pmc.ncbi.nlm.nih.gov
Transcript buffering entails the reciprocal modulation of mRNA synthesis and degradation
rates to maintain stable RNA levels under varying cellular conditions. Current research …

Gene-specific RNA homeostasis revealed by perturbation of the NuA4/Tip60 acetyltransferase complex

F Forouzanfar, D Plassard, A Furst, DF Moreno… - 2024 - hal.science
Transcript buffering entails the reciprocal modulation of mRNA synthesis and degradation
rates, ensuring a constant RNA concentration amidst changes in cellular conditions. While …