Plasma utilization has increased over the past two decades, and there is a growing concern
that many plasma transfusions are inappropriate. Plasma transfusion is not without risk, and …

The transfusion approach to massive hemorrhage has continually evolved since it began in
the early 1900s. It started with fresh whole blood and currently consists of virtually exclusive …

Background Plasma is integral to haemostatic resuscitation after injury, but the timing of
administration remains controversial. Anticipating approval of lyophilised plasma by the US …

Importance Although the Afghanistan and Iraq conflicts have the lowest US case-fatality
rates in history, no comprehensive assessment of combat casualty care statistics, major …

Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient, which when implemented may improve patient outcomes …

Introduction The appropriate strategy for trauma-induced coagulopathy management is
under debate. We report the treatment of major trauma using mainly coagulation factor …

Objective: To determine the effect of blood component ratios in massive transfusion (MT), we
hypothesized that increased use of plasma and platelet to red blood cell (RBC) ratios would …

Background: Increased understanding of the pathophysiology of the acute coagulopathy of
trauma has lead many to question the current transfusion approach to hemorrhagic shock …

BACKGROUND: The use of plasma-based resuscitation for trauma patients in hemorrhagic
shock has been associated with a decrease in mortality. Although some have proposed a …

Background In A fghanistan, a substantial portion of resuscitative combat surgery is
performed by US A rmy forward surgical teams (FST s). Red blood cells (RBC s) and fresh …