DNA polymerases divide the labor of genome replication
SA Lujan, JS Williams, TA Kunkel - Trends in cell biology, 2016 - cell.com
DNA polymerases synthesize DNA in only one direction, but large genomes require RNA
priming and bidirectional replication from internal origins. We review here the physical …
priming and bidirectional replication from internal origins. We review here the physical …
The BioGRID interaction database: 2019 update
R Oughtred, C Stark, BJ Breitkreutz, J Rust… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
The BioGRID interaction database: 2017 update
A Chatr-Aryamontri, R Oughtred, L Boucher… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the annotation and archival …
https://thebiogrid. org) is an open access database dedicated to the annotation and archival …
Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach
O Iborra-Egea, C Gálvez-Montón, S Roura… - NPJ systems biology …, 2017 - nature.com
Sacubitril/Valsartan, proved superiority over other conventional heart failure management
treatments, but its mechanisms of action remains obscure. In this study, we sought to explore …
treatments, but its mechanisms of action remains obscure. In this study, we sought to explore …
[HTML][HTML] FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance
CA Bartel, N Parameswaran, R Cipriano… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The FAM83 proteins were recently identified as novel transforming oncogenes that function
as intermediaries in EGFR/RAS signaling. Using two distinct forward genetics screens, the …
as intermediaries in EGFR/RAS signaling. Using two distinct forward genetics screens, the …
BioGRID: a resource for studying biological interactions in yeast
R Oughtred, A Chatr-aryamontri… - Cold Spring Harbor …, 2016 - cshprotocols.cshlp.org
Abstract The Biological General Repository for Interaction Datasets (BioGRID) is a freely
available public database that provides the biological and biomedical research communities …
available public database that provides the biological and biomedical research communities …
Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast
E Gonçalves, Z Raguz Nakic, M Zampieri… - PLoS computational …, 2017 - journals.plos.org
Cells react to extracellular perturbations with complex and intertwined responses.
Systematic identification of the regulatory mechanisms that control these responses is still a …
Systematic identification of the regulatory mechanisms that control these responses is still a …
Urinary proteome analysis identified neprilysin and VCAM as proteins involved in diabetic nephropathy
E Guillén-Gómez, B Bardají-de-Quixano… - Journal of diabetes …, 2018 - Wiley Online Library
Urinary proteome was analyzed and quantified by tandem mass tag (TMT) labeling followed
by bioinformatics analysis to study diabetic nephropathy (DN) pathophysiology and to …
by bioinformatics analysis to study diabetic nephropathy (DN) pathophysiology and to …
SARNP, a participant in mRNA splicing and export, negatively regulates E‐cadherin expression via interaction with pinin
Triple‐negative breast cancer (TNBC) is associated with a high mortality rate, which is
related to the insufficient number of appropriate biomarkers and targets. Therefore, there is …
related to the insufficient number of appropriate biomarkers and targets. Therefore, there is …
Bioinformatics and microarray analysis of miRNAs in aged female mice model implied new molecular mechanisms for impaired fracture healing
B He, ZK Zhang, J Liu, YX He, T Tang, J Li… - International journal of …, 2016 - mdpi.com
Impaired fracture healing in aged females is still a challenge in clinics. MicroRNAs (miRNAs)
play important roles in fracture healing. This study aims to identify the miRNAs that …
play important roles in fracture healing. This study aims to identify the miRNAs that …