Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Bacterial infections, with the most severe form being sepsis, can often not be treated
adequately leading to high morbidity and lethality of infected patients in critical care units. In …

The most potent cell wall-derived inflammatory toxins (“pathogenicity factors”) of Gram-
negative and-positive bacteria are lipopolysaccharides (LPS)(endotoxins) and lipoproteins …

Shigella spp. causing bacterial diarrhea and dysentery are human enteroinvasive bacterial
pathogens that are orally transmitted through contaminated food and water and cause …

The CRISPR (c lustered r egularly i nterspaced s hort p alindromic r epeat)-Cas system is a
unique genomic entity that provides prokaryotic cells with adaptive and heritable immunity …

The larvae of the insect Galleria mellonella, have recently been established as a non-
mammalian infection model for the Mycobacterium tuberculosis complex (MTBC). To gain …

Aim: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and
dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel …

Cecropins constitute an important family of insect antimicrobial peptides involved in humoral
innate immune response. In comparison with the highly basic cecropins A and B, cecropins …

Context: HuanglianJiedu decoction (HJD) is a classic prescription for heat-clearing away
and detoxifying, which is used for the clinical treatment of sepsis, due to sepsis refers to the …

The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is a
unique genomic entity that provides prokaryotic cells with adaptive and heritable immunity …