Long-term exposure to arsenic (inorganic arsenic) is a world-wide environmental health
concern. Arsenic is classified as the Group 1 human carcinogen by the International Agency …

Human exposure to inorganic arsenic (iAs) is a global health issue. Although there is strong
evidence for iAs‐induced toxicity at higher levels of exposure, many epidemiological studies …

Arsenic in drinking water impacts health. Highest levels of arsenic have been historically
observed in Taiwan and Bangladesh but the contaminant has been affecting the health of …

The biologic effects of inorganic arsenic predominantly involve reaction of the trivalent forms
with sulfhydryl groups in critical proteins in target cells, potentially leading to various …

As a well-established human carcinogen, arsenic has increased the risk of lung cancer over
the past decades. Wide exposure to arsenic in the environment has attracted the attention of …

Arsenic, cadmium, nickel and hexavalent chromium are among the most common
environmental pollutants and potent carcinogens. Chronic exposure to these metals causes …

Xenobiotics, of which many are toxic, may enter the human body through multiple routes.
Excessive human exposure to xenobiotics may exceed the body's capacity to defend against …

Inorganic arsenic induces a variety of toxicities including cancer. The mode of action for
cancer and non-cancer effects involves the metabolic generation of trivalent arsenicals and …

Background: Arsenic exposure affects> 200 million people worldwide, including> 50 million
in Bangladesh. Arsenic exposure increases the risk of cancer and other chronic diseases …

The linear no-threshold (LNT) model has historically been the default assumption in
assessing carcinogenic risk from arsenic ingestion based on epidemiological studies. This …