The Ugi three-component reaction and its variants

JC Flores-Reyes, A Islas-Jácome… - Organic Chemistry …, 2021 - pubs.rsc.org
More than 60 years have passed since I. Ugi synthesized the first α-amidoamides in one
experimental step involving a combination of aldehydes, amines, carboxylic acids and …

The Groebke‐Blackburn‐Bienaymé Reaction

A Boltjes, A Dömling - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …

Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review

J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …

Synthesis of heterocyclic analogs of isoflavone and homoisoflavone based on 3-formylchromone

SS Shatokhin, VA Tuskaev, SC Gagieva… - Russian Chemical …, 2021 - Springer
The review is focused on recent developments of chemistry of synthetic analogs of natural
compounds, isoflavone and homoisoflavone. The possible synthetic strategies to access …

One‐Pot Construction of Bis‐Heterocycles through Isocyanide Based Multicomponent Reactions

S Ishwar Bhat - ChemistrySelect, 2020 - Wiley Online Library
Bis‐heterocycles (BHCs) are hybrid molecules comprising two linked, bound, spacer, or
fused heterocyclic skeletons. In recent years, these compounds have attracted increased …

Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs

WS Hamama, ME Ibrahim, AA Gooda, HH Zoorob - RSC advances, 2018 - pubs.rsc.org
This review highlights the recently cited research data in the literature on the chemistry of 2-
chloroquinoline-3-carbaldehyde and related analogs and their applications over the period …

α-Aminoazoles/azines: key reaction partners for multicomponent reactions

S Imtiaz, S Banoo - RSC advances, 2021 - pubs.rsc.org
Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration
by researchers owing to their key role in diverse biological and physiological processes. The …

Choline chloride/urea as a deep eutectic solvent/organocatalyst promoted three-component synthesis of 3-aminoimidazo-fused heterocycles via Groebke–Blackburn …

A Shaabani, SE Hooshmand - Tetrahedron Letters, 2016 - Elsevier
The catalytic activity of urea-, metal-and organic acid-based/choline chloride deep eutectic
solvents/organocatalysts was investigated for the synthesis of 3-aminoimidazo-fused …

Solvent- and Catalyst-Free One-Pot Green Bound-Type Fused Bis-Heterocycles Synthesis via Groebke–Blackburn–Bienaymé Reaction/SNAr/Ring-Chain Azido …

MA Claudio-Catalán, SG Pharande… - ACS …, 2018 - ACS Publications
A new, efficient, green, endogenous water-triggered, solvent-and catalyst-free ultrasound-
assisted one-pot Groebke–Blackburn–Bienaymé reaction/SNAr/ring-chain azido …

An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction

SG Balwe, YT Jeong - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
A concise and efficient one-pot synthesis of novel N-fused tricyclic derivatives has been
developed by using the Groebke–Blackburn–Bienaymé (GBB) reaction, which involved the …