Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …

Cellular metabolism constitutes a fundamental process in biology. During tumor initiation
and progression, each cellular component in the cancerous niche undergoes dramatic …

Cancer cells evade T cell-mediated killing through tumour–immune interactions whose
mechanisms are not well understood,. Dendritic cells (DCs), especially type-1 conventional …

It is being increasingly acknowledged that immune cells depend on certain metabolic traits
to perform their functions and that the extracellular environment can influence cell …

Abnormal intracellular metabolism not only provides nutrition for tumor occurrence and
development, but also sensitizes the function of various immune cells in the immune …

Dendritic cells (DCs) are highly susceptible to extrinsic signals that modify the functions of
these crucial APCs. Maturation of DCs induced by diverse proinflammatory conditions …

Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that are essential in
mediating the body's natural and adaptive immune responses. The body can regulate the …

Graft versus host disease (GVHD) is a common complication and the leading cause of
morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

Abstract Background Live kinase B1 (LKB1) is a tumor suppressor, which is mutated in
Peutz-Jeghers syndrome (PJS) and in a variety of cancers. Lkb1 encodes serine-threonine …

Dendritic cells (DCs) are innate immune cells that detect and process environmental signals
and communicate them with T cells to bridge innate and adaptive immunity. Immune signals …