Biomaterial strategies for alleviation of myocardial infarction

JR Venugopal, MP Prabhakaran… - Journal of the …, 2012 - royalsocietypublishing.org
World Health Organization estimated that heart failure initiated by coronary artery disease
and myocardial infarction (MI) leads to 29 per cent of deaths worldwide. Heart failure is one …

Insulin, Ascorbate, and Glucose Have a Much Greater Influence Than Transferrin and Selenous Acid on the In Vitro Growth of Engineered Cartilage in Chondrogenic …

AD Cigan, RJ Nims, MB Albro, JD Esau… - … Engineering Part A, 2013 - liebertpub.com
The primary goal of this study was to characterize the response of chondrocyte-seeded
agarose constructs to varying concentrations of several key nutrients in a chondrogenic …

Nanoengineering gold particle composite fibers for cardiac tissue engineering

M Shevach, BM Maoz, R Feiner, A Shapira… - Journal of Materials …, 2013 - pubs.rsc.org
Gold nanostructures can be incorporated into macroporous scaffolds to increase the matrix
conductivity and enhance the electrical signal transfer between cardiac cells. Here we report …

Scaffold stiffness affects the contractile function of three‐dimensional engineered cardiac constructs

A Marsano, R Maidhof, LQ Wan, Y Wang… - Biotechnology …, 2010 - Wiley Online Library
We investigated the effects of the initial stiffness of a three‐dimensional elastomer scaffold—
highly porous poly (glycerol sebacate)—on functional assembly of cardiomyocytes cultured …

Perfusion seeding of channeled elastomeric scaffolds with myocytes and endothelial cells for cardiac tissue engineering

R Maidhof, A Marsano, EJ Lee… - Biotechnology …, 2010 - Wiley Online Library
The requirements for engineering clinically sized cardiac constructs include medium
perfusion (to maintain cell viability throughout the construct volume) and the protection of …

Mechanical characterization and non-linear elastic modeling of poly (glycerol sebacate) for soft tissue engineering

AG Mitsak, AM Dunn, SJ Hollister - Journal of the mechanical behavior of …, 2012 - Elsevier
Scaffold tissue engineering strategies for repairing and replacing soft tissue aim to improve
reconstructive and corrective surgical techniques whose limitations include suboptimal …

Immunobiology of fibrin-based engineered heart tissue

L Conradi, S Schmidt, E Neofytou… - Stem cells …, 2015 - academic.oup.com
Different tissue-engineering approaches have been developed to induce and promote
cardiac regeneration; however, the impact of the immune system and its responses to the …

Multimodal biomaterial strategies for regeneration of infarcted myocardium

S Mukherjee, JR Venugopal, R Ravichandran… - Journal of Materials …, 2010 - pubs.rsc.org
Myocardial tissue engineering (MTE) is an exciting front of research which is both highly
competitive and extremely challenging for researchers. MTE aims to attenuate the functional …

Establishing early functional perfusion and structure in tissue engineered cardiac constructs

B Wang, SS Patnaik, B Brazile, JR Butler… - Critical Reviews™ in …, 2015 - dl.begellhouse.com
Myocardial infarction (MI) causes massive heart muscle death and remains a leading cause
of death in the world. Cardiac tissue engineering aims to replace the infarcted tissues with …

Electrical Stimulation Optimization in Bioreactors for Tissue Engineering Applications

P Pascoal-Faria, P Castelo Ferreira… - Applied Mechanics …, 2019 - Trans Tech Publ
We review here the current research status on bioreactors for tissue engineering with cell
electrical stimulation. Depending on the cell types, electrical stimulation has distinct …