Chronic obstructive pulmonary disease (COPD) is a debilitating heterogeneous disease
characterised by unregulated proteolytic destruction of lung tissue mediated via a protease …

The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

Background Many cases of placenta accreta spectrum are not diagnosed antenatally,
despite identified risk factors and improved imaging methods. Identification of plasma …

Abstract Background and Objective Interleukin 6 (IL-6) has been identified as a key mediator
in inflammation, immune responses and glucose metabolism. In this study, we assessed the …

Acute kidney injury (AKI) is a serious complication of sepsis with a rapid onset and high
mortality rate. Bavachin, an active component of Psoralea corylifolia L., reportedly has …

The gene SerpinC1 encodes a serine protease inhibitor named antithrombin III (ATIII). This
protease demonstrates both anticoagulant and anti-inflammatory action. ATIII is the most …

Intestinal ischemia followed by reperfusion leads to local and remote organ injury attributed
to inflammatory response during the reperfusion phase. The extent to which ischemia …

Background In spite of extensive study, the mechanisms for salt sensitivity of BP in humans
and rodent models remain poorly understood. Several microRNAs (miRNAs) have been …

Cardiorenal syndrome type 3 (CRS-3) is damage to the heart following acute kidney injury
(AKI). Although many experiments have found that inflammation, oxidative stress, and …

Oxidative stress and inflammation have been demonstrated to be involved in the onset and
promotion of diabetic nephropathy (DN). Tanshinone IIA (Tan) possesses both antioxidant …