Frontiers of chaotic advection

H Aref, JR Blake, M Budišić, SSS Cardoso… - Reviews of Modern …, 2017 - APS
This work reviews the present position of and surveys future perspectives in the physics of
chaotic advection: the field that emerged three decades ago at the intersection of fluid …

A multiscale biophysical model gives quantized metachronal waves in a lattice of beating cilia

B Chakrabarti, S Fürthauer… - Proceedings of the …, 2022 - National Acad Sciences
Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the
action of internal molecular motors and are typically found in dense arrays. These active …

Symmetry-breaking cilia-driven flow in embryogenesis

DJ Smith, TD Montenegro-Johnson… - Annual Review of Fluid …, 2019 - annualreviews.org
The systematic breaking of left–right body symmetry is a familiar feature of human
physiology. In humans and many animals, this process originates with asymmetric fluid flow …

Left-right organizer flow dynamics: how much cilia activity reliably yields laterality?

P Sampaio, RR Ferreira, A Guerrero, P Pintado… - Developmental cell, 2014 - cell.com
Internal organs are asymmetrically positioned inside the body. Embryonic motile cilia play
an essential role in this process by generating a directional fluid flow inside the vertebrate …

Assessing the collective dynamics of motile cilia in cultures of human airway cells by multiscale DDM

L Feriani, M Juenet, CJ Fowler, N Bruot, M Chioccioli… - Biophysical journal, 2017 - cell.com
The technique of differential dynamic microscopy is extended here, showing that it can
provide a powerful and objective method of video analysis for optical microscopy videos of …

[HTML][HTML] A nearest-neighbour discretisation of the regularized stokeslet boundary integral equation

DJ Smith - Journal of Computational Physics, 2018 - Elsevier
The method of regularized stokeslets is extensively used in biological fluid dynamics due to
its conceptual simplicity and meshlessness. This simplicity carries a degree of cost in …

Cilia and centrosomes: Ultrastructural and mechanical perspectives

T Ishikawa, H Ueno, T Omori, K Kikuchi - Seminars in Cell & …, 2021 - Elsevier
Cilia and centrosomes of eukaryotic cells play important roles in cell movement, fluid
transport, extracellular sensing, and chromosome division. The physiological functions of …

A regularised singularity approach to phoretic problems

TD Montenegro-Johnson, S Michelin… - The European Physical …, 2015 - Springer
An efficient, accurate, and flexible numerical method is proposed for the solution of the
swimming problem of one or more autophoretic particles in the purely diffusive limit. The …

Kupffer's vesicle size threshold for robust left–right patterning of the zebrafish embryo

JJ Gokey, Y Ji, HG Tay, B Litts… - Developmental …, 2016 - Wiley Online Library
Background: Motile cilia in the “organ of asymmetry” create directional fluid flows that are
vital for left–right (LR) asymmetric patterning of vertebrate embryos. Organ function often …

Dynamics of cilia length in left–right development

P Pintado, P Sampaio, B Tavares… - Royal Society …, 2017 - royalsocietypublishing.org
Reduction in the length of motile cilia in the zebrafish left–right organizer (LRO), also known
as Kupffer's vesicle, has a large impact on left–right development. Here we demonstrate …