Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the
prevalence patterns of asexual parasites in people of different ages, whereas the …

Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

Sexually reproducing parasites, such as malaria parasites, experience a trade-off between
the allocation of resources to asexual replication and the production of sexual forms …

Malaria morbidity and mortality continue to increase across sub-Saharan Africa. This is
largely as a result of the continued use of chloroquine and sulfadoxine-pyrimethamine …

Background. Although malaria treatment aims primarily to eliminate the asexual blood
stages that cause illness, reducing the carriage of gametocytes is critical for limiting malaria …

Background Although malaria control intervention has greatly decreased malaria morbidity
and mortality in many African countries, further decline in parasite prevalence has stagnated …

Background The aim of this study was to identify and compare factors associated with
Plasmodium falciparum gametocyte carriage in three regions of differing malaria endemicity …