Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …

One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged
symptoms termed long coronavirus disease (COVID), yet disease phenotypes and …

Abstract Changes in the transcriptomes of human tissues with advancing age are poorly
cataloged. Here, we sought to identify the coding and long noncoding RNAs present in …

Background Lymphopenia and the neutrophil/lymphocyte ratio may have prognostic value in
COVID-19 severity. Objective We investigated neutrophil subsets and functions in blood and …

Despite its major role in complex human functions across the lifespan, most notably
navigation, learning and memory, much of the genetic architecture of the hippocampal …

Background Pharmacogenetic studies in asthma cohorts, primarily made up of White people
of European descent, have identified loci associated with response to inhaled beta agonists …

Chronic tissue injury triggers changes in the cell type and microenvironment at the site of
injury and eventually fibrosis develops. Current research suggests that fibrosis is a highly …

Adipose tissue homeostasis plays a central role in cardiovascular physiology, and the
presence of thermogenically active brown adipose tissue (BAT) has recently been …

Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent
evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical …