Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …

Cell identity is maintained by activation of cell-specific gene programs, regulated by
epigenetic marks, transcription factors and chromatin organization. DNA G-quadruplex (G4) …

G-quadruplexes (G4s) are noncanonical nucleic acid structures involved in the regulation of
key cellular processes, such as transcription and replication. Since their discovery, G4s have …

Viruses are the most abundant organisms on our planet, affecting all living beings: some of
them are responsible for massive epidemics that concern health, national economies and …

G-quadruplexes are non-canonical nucleic-acid structures that control transcription,
replication, and recombination in organisms. G-quadruplexes are present in eukaryotes …

A G-quadruplex (G4) is a four-stranded nucleic acid secondary structure maintained by
Hoogsteen hydrogen bonds established between four guanines. Experimental studies and …

With the emergence of new viruses in the human population and the fast mutation rates of
existing viruses, new antiviral targets and compounds are needed. Most existing antiviral …

G-quadruplexes (G4s) are noncanonical nucleic acid secondary structures formed by
guanine-rich DNA and RNA sequences. In this review we aim to provide an overview of the …

Abstract G-quadruplex (G4) is a unique secondary structure formed by guanine-rich nucleic
acid sequences. Growing studies reported that the genomes of some viruses harbor G4 …

Organic small molecules that can recognize and bind to G-quadruplex and i-Motif nucleic
acids have great potential as selective drugs or as tools in drug target discovery programs …