Chemotherapeutic antibiotic doxorubicin belongs to the anthracycline class, slaughters not
only the cancer cells but also non-cancerous cells even in the non-targeted organs thereby …

Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …

There has been a lot of interest in using naturally occurring substances to treat a wide
variety of chronic disorders in recent years. From the gum resin of Boswellia serrata and …

The present investigation has been undertaken to reveal the protective mechanism of
polyphenolics extract of whole wheat grains (WWGPE), ferulic acid and apigenin against …

Although Doxorubicin (DOX) is a widespread drug used in the treatment of cancer, its
clinical use is restricted due to its common side effects. In addition, administrating DOX with …

Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

This study evaluated if the hepatic protective effect of Isoliquiritigenin (ISL) against
doxorubicin (DOX)-treated rats involves upregulating sirtuin-1 (SIRT1) signaling. Adult male …

As one classic anticancer drug, clinical application of Doxorubicin (Dox) is limited due to its
side effects. In our previous work, we have investigated the drug targets to treat Dox-induced …

For the treatment of diseases, especially chronic diseases, traditional natural drugs have
more effective therapeutic advantages because of their multi-target and multi-channel …