Roles of CA19-9 in pancreatic cancer: Biomarker, predictor and promoter

G Luo, K Jin, S Deng, H Cheng, Z Fan, Y Gong… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Carbohydrate antigen 19-9 (CA19-9) is the best validated biomarker and an
indicator of aberrant glycosylation in pancreatic cancer. CA19-9 functions as a biomarker …

Novel diagnostic and predictive biomarkers in pancreatic adenocarcinoma

JC Chang, M Kundranda - International journal of molecular sciences, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease for a multitude of
reasons including very late diagnosis. This in part is due to the lack of understanding of the …

[HTML][HTML] Factors predicting response, perioperative outcomes, and survival following total neoadjuvant therapy for borderline/locally advanced pancreatic cancer

MJ Truty, ML Kendrick, DM Nagorney, RL Smoot… - Annals of …, 2021 - journals.lww.com
Objective: To identify predictive factors associated with operative morbidity, mortality, and
survival outcomes in patients with borderline resectable (BR) or locally advanced (LA) …

FDG-PET predicts neoadjuvant therapy response and survival in borderline resectable/locally advanced pancreatic adenocarcinoma

AM Abdelrahman, AH Goenka, R Alva-Ruiz… - Journal of the National …, 2022 - jnccn.org
Background: Neoadjuvant therapy (NAT) is used in borderline resectable/locally advanced
(BR/LA) pancreatic ductal adenocarcinoma (PDAC). Anatomic imaging (CT/MRI) poorly …

A multianalyte panel consisting of extracellular vesicle miRNAs and mRNAs, cfDNA, and CA19-9 shows utility for diagnosis and staging of pancreatic ductal …

Z Yang, MJ LaRiviere, J Ko, JE Till, T Christensen… - Clinical Cancer …, 2020 - AACR
Purpose: To determine whether a multianalyte liquid biopsy can improve the detection and
staging of pancreatic ductal adenocarcinoma (PDAC). Experimental Design: We analyzed …

Tumor heterogeneity of pancreas head cancer assessed by CT texture analysis: association with survival outcomes after curative resection

G Yun, YH Kim, YJ Lee, B Kim, JH Hwang, DJ Choi - Scientific reports, 2018 - nature.com
The value of image based texture features as a powerful method to predict prognosis and
assist clinical management in cancer patients has been established recently. However …

[HTML][HTML] Carcinoembryonic antigen, carbohydrate antigen 19-9, cancer antigen 125, prostate-specific antigen and other cancer markers: a primer on commonly used …

S Desai, AK Guddati - World Journal of Oncology, 2023 - ncbi.nlm.nih.gov
Cancer markers are molecules produced by cancer cells which may serve to identify the
presence of cancer. Cancer markers can be differentiated as serum-based, radiology-based …

Preoperative chemotherapy, radiotherapy and surgical decision-making in patients with borderline resectable and locally advanced pancreatic cancer

TF Stoop, RT Theijse, LWF Seelen… - Nature Reviews …, 2024 - nature.com
Surgical resection combined with systemic chemotherapy is the cornerstone of treatment for
patients with localized pancreatic cancer. Upfront surgery is considered suboptimal in cases …

Elevated glypican‐1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma

H Lu, F Niu, F Liu, J Gao, Y Sun, X Zhao - Cancer medicine, 2017 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer in humans, with a 5‐
year survival rate of< 5%. Recently, glypican‐1 (GPC1)‐expressing circulating exosomes …

Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study

HC Kung, J Yu - MedComm, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy with a
high rate of recurrence and a dismal 5‐year survival rate. Contributing to the poor prognosis …