A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning
Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain;
however, their function is rather heterogeneous in respect to their origin, location …
however, their function is rather heterogeneous in respect to their origin, location …
Multiple sclerosis and the endogenous opioid system
Z Dworsky-Fried, CI Chadwick, BJ Kerr… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation,
neuronal degeneration and demyelinating lesions within the central nervous system. The …
neuronal degeneration and demyelinating lesions within the central nervous system. The …
[HTML][HTML] Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives
M García-Domínguez - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Enkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain
modulation. Enkephalins primarily exert their effects through opioid receptors located widely …
modulation. Enkephalins primarily exert their effects through opioid receptors located widely …
Ceramide kinase knockout ameliorates multiple sclerosis-like behaviors and demyelination in cuprizone-treated mice
A Tanaka, K Anada, M Yasue, T Honda, H Nakamura… - Life Sciences, 2022 - Elsevier
Abstract Changes in sphingolipid metabolism regulate and/or alter many cellular functions in
the brain. Ceramide, a central molecule of sphingolipid metabolism, is phosphorylated to …
the brain. Ceramide, a central molecule of sphingolipid metabolism, is phosphorylated to …
Electroacupuncture at ST36 acupoint regulates stem cells during experimental autoimmune encephalomyelitis
X Chen, Y Wang, J Ji, C Li, W Zhuang, J Luo… - International …, 2023 - Elsevier
Background Electroacupuncture (EA) is given to assist in the treatment of MS, which is an
effective therapeutic method. However, the therapy mechanism of EA related to stem cells in …
effective therapeutic method. However, the therapy mechanism of EA related to stem cells in …
Timing of treatment with an endogenous opioid alters immune response and spinal cord pathology in female mice with experimental autoimmune encephalomyelitis
C Patel, IS Zagon, M Pearce‐Clawson… - Journal of …, 2022 - Wiley Online Library
Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that
primarily affects women during the second or third decade of life. The mechanism is …
primarily affects women during the second or third decade of life. The mechanism is …
[图书][B] Clinical and Morphological Manifestations of Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis Resulting from Modulation of Endogenous …
CL Patel - 2021 - search.proquest.com
Multiple Sclerosis (MS) is an autoimmune, progressive demyelinating disorder specific to the
central nervous system initially described in 1868 by Jean-Martin Charcot. Initial accounts of …
central nervous system initially described in 1868 by Jean-Martin Charcot. Initial accounts of …