Pluripotent stem cell-based gene therapy approach: Human de novo synthesized chromosomes
SA Sinenko, SV Ponomartsev, AN Tomilin - Cellular and Molecular Life …, 2021 - Springer
A novel approach in gene therapy was introduced 20 years ago since artificial non-
integrative chromosome-based vectors containing gene loci size inserts were engineered …
integrative chromosome-based vectors containing gene loci size inserts were engineered …
[HTML][HTML] Gene expressing human artificial chromosome vectors: Advantages and challenges for gene therapy
D Moralli, ZL Monaco - Experimental Cell Research, 2020 - Elsevier
After the construction of genomic libraries with yeast artificial chromosomes in the late
1980's for gene isolation and expression studies in cells, human artificial chromosomes …
1980's for gene isolation and expression studies in cells, human artificial chromosomes …
Episomes and Transposases—Utilities to Maintain Transgene Expression from Nonviral Vectors
F Kreppel, C Hagedorn - Genes, 2022 - mdpi.com
The efficient delivery and stable transgene expression are critical for applications in gene
therapy. While carefully selected and engineered viral vectors allowed for remarkable …
therapy. While carefully selected and engineered viral vectors allowed for remarkable …
From kilobases to megabases: Design and delivery of large DNA constructs into mammalian genomes
FG Liberante, T Ellis - Current Opinion in Systems Biology, 2021 - Elsevier
As DNA synthesis has become cheaper, it has made assembly of larger and larger genes
possible. To fully realise this opportunity for a new era of synthetic biology in mammals, a …
possible. To fully realise this opportunity for a new era of synthetic biology in mammals, a …
Progress and future challenges in gene vectors, gene therapy systems and gene expressions
D Veeman, D Dhamodharan, LT Jule - Indian Journal of …, 2022 - op.niscpr.res.in
Genetic engineering has made sizeable contributions to technical innovation, agriculture,
and the development of pharmaceuticals. Various approaches were evolved to control the …
and the development of pharmaceuticals. Various approaches were evolved to control the …
[HTML][HTML] Human Artificial Chromosomes and Their Transfer to Target Cells
SV Ponomartsev, SA Sinenko, AN Tomilin - Acta Naturae, 2022 - ncbi.nlm.nih.gov
Human artificial chromosomes (HACs) have been developed as genetic vectors with the
capacity to carry large transgenic constructs or entire gene loci. HACs represent either …
capacity to carry large transgenic constructs or entire gene loci. HACs represent either …
[HTML][HTML] Искусственные хромосомы человека и способы их доставки в клетки-мишени
СВ Пономарцев, СА Синенко… - Acta Naturae …, 2022 - cyberleninka.ru
Искусственные хромосомы человека разработаны в качестве генетических векторов,
позволяющих нести большие трансгенные конструкции или целые генные локусы …
позволяющих нести большие трансгенные конструкции или целые генные локусы …
ACTA NATURAE (АНГЛОЯЗЫЧНАЯ ВЕРСИЯ)
SV Ponomartsev, SA Sinenko, AN Tomilin - … ) Учредители: Общество с …, 2022 - elibrary.ru
Human artificial chromosomes (HACs) have been developed as genetic vectors with the
capacity to carry large transgenic constructs or entire gene loci. HACs represent either …
capacity to carry large transgenic constructs or entire gene loci. HACs represent either …
Распознающие cкаффолдовые полипептиды как инструмент для адресной доставки наноструктур in vitro и in vivo
ВО Шипунова, СМ Деев - elibrary.ru
Традиционные средства адресной доставки наноструктур, такие, как антитела,
трансферрин, лектины или аптамеры, зачастую могут вызывать целый спектр …
трансферрин, лектины или аптамеры, зачастую могут вызывать целый спектр …