The health of children conceived by ART:'the chicken or the egg?'

S Berntsen, V Söderström-Anttila… - Human reproduction …, 2019 - academic.oup.com
Worldwide, more than 7 million children have now been born after ART: these delivery rates
are steadily rising and now comprise 2–6% of births in the European countries. To achieve …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection

SL Boulet, A Mehta, DM Kissin, L Warner, JF Kawwass… - Jama, 2015 - jamanetwork.com
Importance Intracytoplasmic sperm injection (ICSI) is increasingly used in patients without
severe male factor infertility without clear evidence of a benefit over conventional in vitro …

Genetics of male infertility

C Krausz, V Rosta, RS Swerdloff, C Wang - Emery and rimoin's principles …, 2022 - Elsevier
Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …

Male infertility: pathogenesis and clinical diagnosis

C Krausz - Best practice & research Clinical endocrinology & …, 2011 - Elsevier
Infertility affects about 7% of all men. The etiology of impaired sperm production and function
can be related to factors acting at pre-testicular, post-testicular or directly at the testicular …

Retired: pregnancy outcomes after assisted reproductive technology

VM Allen, RD Wilson, A Cheung, C Blight… - Journal of obstetrics and …, 2006 - Elsevier
Objective: To review the effect of assisted reproductive technology (ART) on perinatal
outcomes, to provide guidelines to optimize obstetrical management and counselling of …

Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications—a position report

CLR Barratt, RJ Aitken, L Björndahl… - Human …, 2010 - academic.oup.com
This article reports the results of the most recent in a series of EHSRE workshops designed
to synthesize the current state of the field in Andrology and provide recommendations for …

Sperm chromatin structure and male fertility: biological and clinical aspects

J Erenpreiss, M Spano, J Erenpreisa… - Asian journal of …, 2006 - Wiley Online Library
Aim: Sperm chromatin/DNA integrity is essential for the accurate transmission of paternal
genetic information, and normal sperm chromatin structure is important for sperm fertilizing …

Outcome of assisted reproduction

AG Sutcliffe, M Ludwig - The Lancet, 2007 - thelancet.com
In-vitro fertilisation has been done for nearly 30 years; in developed countries at least 1% of
births are from assisted reproductive therapies (ART). These children now represent a …

[HTML][HTML] “Physiologic ICSI”: hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of …

L Parmegiani, GE Cognigni, S Bernardi, E Troilo… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the role of hyaluronic acid (HA) for sperm selection before
intracytoplasmic sperm injection (ICSI). DESIGN: Three prospective studies. SETTING …