Anatomy of the larynx and cervical trachea

KL McCullagh, RN Shah… - Neuroimaging …, 2022 - neuroimaging.theclinics.com
The larynx is an anatomically complex organ of the upper airway that lies at the crossroads
of the upper aerodigestive tract and the tracheobronchial tree. It connects the pharynx with …

[HTML][HTML] Brainstem and spinal cord MRI identifies altered sensorimotor pathways post-stroke

H Karbasforoushan, J Cohen-Adad… - Nature …, 2019 - nature.com
Damage to the corticospinal tract is widely studied following unilateral subcortical stroke,
whereas less is known about changes to other sensorimotor pathways. This may be due to …

Electrospun drug‐loaded scaffolds for nervous system repair

SC Kellaway, MM Ullrich… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Nervous system injuries, encompassing peripheral nerve injury (PNI), spinal cord injury
(SCI), and traumatic brain injury (TBI), present significant challenges to patients' wellbeing …

[HTML][HTML] Rapid, automated nerve histomorphometry through open-source artificial intelligence

SC Daeschler, MH Bourget, D Derakhshan… - Scientific Reports, 2022 - nature.com
We aimed to develop and validate a deep learning model for automated segmentation and
histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A …

Human spinal oligodendrogenic neural progenitor cells enhance pathophysiological outcomes and functional recovery in a clinically relevant cervical spinal cord …

K Pieczonka, H Nakashima, N Nagoshi… - Stem Cells …, 2023 - academic.oup.com
Traumatic spinal cord injury (SCI) results in the loss of neurons, oligodendrocytes, and
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …

Imaging G-ratio in multiple sclerosis using high-gradient diffusion MRI and macromolecular tissue volume

F Yu, Q Fan, Q Tian, C Ngamsombat… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Remyelination represents an area of great therapeutic
interest in multiple sclerosis but currently lacks a robust imaging marker. The purpose of this …

[HTML][HTML] Temporal Diffusion Ratio (TDR) for imaging restricted diffusion: Optimisation and pre-clinical demonstration

W Warner, M Palombo, R Cruz, R Callaghan… - NeuroImage, 2023 - Elsevier
Abstract Temporal Diffusion Ratio (TDR) is a recently proposed dMRI technique (Dell'Acqua
et al., proc. ISMRM 2019) which provides contrast between areas with restricted diffusion …

Relevance of time‐dependence for clinically viable diffusion imaging of the spinal cord

F Grussu, A Ianuş, C Tur, F Prados… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose Time‐dependence is a key feature of the diffusion‐weighted (DW) signal,
knowledge of which informs biophysical modelling. Here, we study time‐dependence in the …

Diffusion MRI microstructural models in the cervical spinal cord–application, normative values, and correlations with histological analysis

KG Schilling, HR Feiler, BA Box, KP O'Grady, A Witt… - NeuroImage, 2019 - Elsevier
Multi-compartment tissue modeling using diffusion magnetic resonance imaging has proven
valuable in the brain, offering novel indices sensitive to the tissue microstructural …

[HTML][HTML] Viscoelastic damage evaluation of the axon

F Hasan, KAHA Mahmud, MI Khan… - … in Bioengineering and …, 2022 - frontiersin.org
In this manuscript, we have studied the microstructure of the axonal cytoskeleton and
adopted a bottom-up approach to evaluate the mechanical responses of axons. The …