• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The aim of this ESC Guideline is to help health professionals manage people with heart
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …

Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Coordinator)(Netherlands),
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …

Excessive trabeculation, often referred to as “noncompacted” myocardium, has been
described at all ages, from the fetus to the adult. Current evidence for myocardial …

O sedentarismo, que apresenta elevada prevalência no Brasil e no mundo, está fortemente
relacionado às doenças cardiovasculares (DCV) e à mortalidade precoce. 7 7. Ding D …

Background Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to
5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and …

Background: Although left ventricular noncompaction (LVNC) has been associated with an
increased risk of adverse cardiovascular events, the accurate incidence of cardiovascular …

Mutations of Lamin A/C gene (LMNA) cause laminopathies, a group of disorders associated
with a wide spectrum of clinically distinct phenotypes, affecting different tissues and organs …

Background Variants in the cardiomyocyte-specific RNA splicing factor RBM20 have been
linked to familial cardiomyopathy, but the causative genetic architecture and clinical …

Background The prognosis of left ventricular noncompaction (LVNC) remains elusive
despite its recognition as a clinical entity for> 30 years. We sought to identify clinical and …