MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …

Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …

An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …

J. Neurochem.(2011) 116, 1–9. Abstract Since its initial characterization over 20 years ago,
there has been intense and unwavering interest in understanding the role of the …

Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …

Alzheimer's disease (AD) and related tauopathies comprise a large group of
neurodegenerative diseases associated with the pathological aggregation of tau protein …

MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …

During the last two decades, microRNAs (miRNAs) emerged as critical regulators of gene
expression. By modulating the expression of numerous target mRNAs mainly at the post …

Alzheimer's disease (AD) is a multifactorial and fatal neurodegenerative disorder for which
the mechanisms leading to profound neuronal loss are incompletely recognized. MicroRNAs …