Bcl-2-associated X protein (BAX) is a critical executioner of mitochondrial regulated cell
death through its lethal activity of permeabilizing the mitochondrial outer membrane (MOM) …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Inflammasomes are cytosolic innate immune complexes that activate caspase-1 following
detection of pathogenic and endogenous dangers,,,–, and NACHT-, leucine-rich repeat …

Plant intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) detect pathogen
effectors to trigger immune responses. Indirect recognition of a pathogen effector by the …

INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

Summary The NACHT-, leucine-rich-repeat-(LRR), and pyrin domain-containing protein 3
(NLRP3) is emerging to be a critical intracellular inflammasome sensor of membrane …

INTRODUCTION Nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs)
mediate plant immunity by directly or indirectly sensing pathogen effector proteins delivered …

INTRODUCTION Nucleotide-binding (NB), leucine-rich repeat (LRR) receptor (NLR)
proteins constitute a family of intracellular immune receptors in both animals and plants that …

This chapter describes algorithmic advances in the RELION software, and how these are
used in high-resolution cryo-electron microscopy (cryo-EM) structure determination. Since …

To counter pathogen invasion, plants have evolved a large number of immune receptors,
including membrane-resident pattern recognition receptors (PRRs) and intracellular …