Olfactory immunology: the missing piece in airway and CNS defence
SA Wellford, EA Moseman - Nature Reviews Immunology, 2024 - nature.com
The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …
Recent studies point to an important role for the olfactory mucosa as a barrier to both …
Neuroinflammation in neurodegeneration via microbial infections
Recent epidemiological studies show a noticeable correlation between chronic microbial
infections and neurological disorders. However, the underlying mechanisms are still not …
infections and neurological disorders. However, the underlying mechanisms are still not …
Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk
Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
Differences in gut microbiota correlate with symptoms and regional brain volumes in patients with late-life depression
CF Tsai, CH Chuang, YP Wang, YB Lin… - Frontiers in Aging …, 2022 - frontiersin.org
Depression is associated with gut dysbiosis that disrupts a gut-brain bidirectional axis. Gray
matter volume changes in cortical and subcortical structures, including prefrontal regions …
matter volume changes in cortical and subcortical structures, including prefrontal regions …
Phagocytosis by peripheral glia: Importance for nervous system functions and implications in injury and disease
The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …
Multinucleated giant cell formation as a portal to chronic bacterial infections
JL Stockton, AG Torres - Microorganisms, 2020 - mdpi.com
This review provides a snapshot of chronic bacterial infections through the lens of
Burkholderia pseudomallei and detailing its ability to establish multi-nucleated giant cells …
Burkholderia pseudomallei and detailing its ability to establish multi-nucleated giant cells …
In Vitro Roles of Burkholderia Intracellular Motility A (BimA) in Infection of Human Neuroblastoma Cell Line
N Jitprasutwit, A Rungruengkitkun… - Microbiology …, 2023 - Am Soc Microbiol
The bacterial pathogen Burkholderia pseudomallei causes human melioidosis, which can
infect the brain, leading to encephalitis and brain abscesses. Infection of the nervous system …
infect the brain, leading to encephalitis and brain abscesses. Infection of the nervous system …
Cycle-Inhibiting Factor Is Associated with Burkholderia pseudomallei Invasion in Human Neuronal Cells
A Rungruengkitkun, N Jitprasutwit, W Muangkaew… - Biology, 2022 - mdpi.com
Simple Summary Neurological melioidosis, caused by Burkholderia pseudomallei, can lead
to the development of severe symptoms associated with the nervous system. However, the …
to the development of severe symptoms associated with the nervous system. However, the …
[HTML][HTML] Virulence of Burkholderia pseudomallei ATS2021 Unintentionally Imported to United States in Aromatherapy Spray
CK Cote, KD Mlynek, CP Klimko… - Emerging Infectious …, 2024 - pmc.ncbi.nlm.nih.gov
In the United States in 2021, an outbreak of 4 cases of Burkholderia pseudomallei, the
etiologic agent of melioidosis and a Tier One Select Agent (potential for deliberate misuse …
etiologic agent of melioidosis and a Tier One Select Agent (potential for deliberate misuse …
Type VI Secretion System Accessory Protein TagAB-5 Promotes Burkholderia pseudomallei Pathogenicity in Human Microglia
S Lohitthai, A Rungruengkitkun, N Jitprasutwit… - Biomedicines, 2023 - mdpi.com
Central nervous system (CNS) melioidosis caused by Burkholderia pseudomallei is being
increasingly reported. Because of the high mortality associated with CNS melioidosis …
increasingly reported. Because of the high mortality associated with CNS melioidosis …