Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …

After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

It is well established that IFN-γ is required for the development of experimental cerebral
malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the …

Cerebral malaria (CM) is a complex parasitic disease caused by Plasmodium sp. Failure to
establish an appropriate balance between pro-and anti-inflammatory immune responses is …

Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …

Malaria remains a global health problem causing more than 400,000 deaths annually.
Plasmodium parasites, the causative agents of malaria, replicate asexually in red blood cells …

Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major
cause of morbidity and mortality worldwide, but particularly in tropical, developing countries …

Background Infection with Plasmodium berghei ANKA (PbA) in susceptible mice induces a
syndrome called experimental cerebral malaria (ECM) with severe pathologies occurring in …

Systemic inflammation mediated by Plasmodium parasites is central to malaria disease and
its complications. Plasmodium parasites reside in erythrocytes and can theoretically reach …