Targeting ROS in cancer: rationale and strategies
C Glorieux, S Liu, D Trachootham… - Nature Reviews Drug …, 2024 - nature.com
Reactive oxygen species (ROS) in biological systems are transient but essential molecules
that are generated and eliminated by a complex set of delicately balanced molecular …
that are generated and eliminated by a complex set of delicately balanced molecular …
Transcriptional regulation by Nrf2
Significance: Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that
coordinates the basal and stress-inducible activation of a vast array of cytoprotective genes …
coordinates the basal and stress-inducible activation of a vast array of cytoprotective genes …
Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data
Y Gao, S Shang, S Guo, X Li, H Zhou, H Liu… - Nucleic acids …, 2021 - academic.oup.com
Abstract An updated Lnc2Cancer 3.0 (http://www. bio-bigdata. net/lnc2cancer or http://bio-
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
[HTML][HTML] The functions and unique features of LncRNAs in cancer development and tumorigenesis
K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
[HTML][HTML] Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression
T Sun, Z Wu, X Wang, Y Wang, X Hu, W Qin, S Lu, D Xu… - Oncogene, 2020 - nature.com
Increasing evidence supports that long noncoding RNAs (lncRNAs) act as master regulators
involved in tumorigenesis and development at the N 6-methyladenine (m6A) epigenetic …
involved in tumorigenesis and development at the N 6-methyladenine (m6A) epigenetic …
GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability
The list of long non-coding RNAs (lncRNAs) involved in the p53 pathway of the DNA
damage response is rapidly expanding, but whether lncRNAs have a role in maintaining the …
damage response is rapidly expanding, but whether lncRNAs have a role in maintaining the …
[HTML][HTML] Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer
The transcription factor NRF2 is a master regulator of the cellular antioxidant response, and
it is often genetically activated in non-small-cell lung cancers (NSCLCs) by, for instance …
it is often genetically activated in non-small-cell lung cancers (NSCLCs) by, for instance …
Lnc2Cancer v2. 0: updated database of experimentally supported long non-coding RNAs in human cancers
Y Gao, P Wang, Y Wang, X Ma, H Zhi… - Nucleic acids …, 2019 - academic.oup.com
Abstract Lnc2Cancer 2.0 (http://www. bio-bigdata. net/lnc2cancer) is an updated database
that provides comprehensive experimentally supported associations between lncRNAs and …
that provides comprehensive experimentally supported associations between lncRNAs and …
Landscape of noncoding RNA in prostate cancer
The transcriptome of prostate cancer is highly heterogeneous, with noncoding transcripts
being essential players. Long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) are …
being essential players. Long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) are …