Introduction The treatment of human and animal sporotrichosis is often performed with
antifungal agents; however, the emergence of antifungal-resistant strains of Sporothrix …

Sporotrichosis is known as a subacute or chronic infection, which is caused by
thermodimorphic fungi of the genus Sporothrix. It is a cosmopolitan infection, which is more …

The treatment of feline sporotrichosis is a challenge for veterinary clinicians since refractory
cases may occur, due either to patient and/or to pharmacological management errors or due …

Sporotrichosis is an implantation mycosis caused by the dimorphic fungus Sporothrix and
mostly involves cutaneous and subcutaneous tissues and the lymphatic vessels. Among …

Abstract Cytochrome P450 monooxygenases (CYPs/P450s), heme thiolate proteins, are
well known for their role in organisms' primary and secondary metabolism. Research on …

Sporothrix schenckii is a worldwide-distributed thermally dimorphic fungus, which usually
causes a subacute to chronic infection through traumatic implantation or inoculation of its …

The fungal P 450s catalyze vital monooxygenation reactions in primary and secondary
metabolism, which may lead to the production of diverse secondary metabolites. Many of …

Cytochrome P450 monooxygenases (P450s) found in all domains of life are known for their
catalytic versatility and stereo-and regio-specific activity. While the impact of lifestyle on …

The gut microbiota plays an important role in regulating the pharmacokinetics and
pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown …

The impact of lifestyle on shaping the genome content of an organism is a well-known
phenomenon and cytochrome P450 enzymes (CYPs/P450s), heme-thiolate proteins that are …