IL-6 family cytokines are defined by the common use of the signal-transducing receptor
chain glycoprotein 130 (gp130). Increasing evidence indicates that these cytokines are …

Rheumatoid arthritis (RA), a systemic disease, is characterized by a chronic inflammatory
reaction in the synovium of joints and is associated with degeneration of cartilage and …

Decreased expression of the Nlrp3 protein is associated with susceptibility to Crohn's
disease. However, the role of Nlrp3 in colitis has not been characterized. Nlrp3 interacts with …

Acute graft-versus-host disease (GVHD), the major complication of allogeneic bone marrow
transplantation (BMT), limits the application of this curative but toxic therapy. Studies of …

Chemotherapy‐and radiotherapy‐induced oral mucositis represents a therapeutic challenge
frequently encountered in cancer patients. This side effect causes significant morbidity and …

F weights of recombinant human (rh) and murine IL-11 are 19,144 daltons6 and 19,154
daltons, 2 respectively. Mature IRST ISOLATED IN 1990, interleukin-11 (IL-11) has proven to …

Implantation is an intricately timed event necessary in the process of viviparous birth that
allows mammals to nourish and protect their young during early development. Human …

Despite all of the advances in our understanding of the pathophysiology of inflammatory
bowel disease (IBD), we still do not know its cause. Some of the most recently available data …

Alimentary tract (AT) mucositis can be a major problem for patients undergoing cancer
treatment. It has significant clinical and economic consequences and is a major factor that …

Mucositis is an inevitable side-effect of the conditioning regimens used for haematopoietic
stem cell transplantation. The condition is better referred to as mucosal barrier injury (MBI) …